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NIH Planning Grant (R34)

Development and Testing of Novel Interventions to Improve HIV Prevention, Treatment, and Program Implementation for People Who Use Substances

Funds building and pilot-testing an HIV prevention, treatment or services intervention for people who use drugs — behavioural, social, structural or combined.

HIV prevention and treatment work when people can reach them, and people who use drugs are among the least likely to. This notice funds building something that changes that, and finding out early whether it can work at all.

Three stages sit in scope: formative research, intervention development, and pilot-testing.

What is tested at the pilot stage is named precisely, and it is not effectiveness.

Formative research, intervention development and pilot-testing of novel or adapted behavioural, social, structural or combination biomedical and behavioural interventions targeting HIV prevention, treatment or services for people who use drugs, assessing feasibility, tolerability, acceptability and safety. A clinical trial is required.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.16 Mar 2027
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.
Funding pooliThe total budget available across all awards in this round.

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Last verified: 25 Aug 2026Funder reference: PAR-24-329Source: www.grants.gov