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NIH Exploratory/Developmental Research Grant

Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R21)

Funds the exploratory version of the same work on screening tests and treatments for serious newborn conditions.

A condition gets added to a newborn screening panel when two things are true: there is an accurate test for it, and finding it early demonstrably helps. This notice funds building either half.

Two kinds of work are in scope. Novel screening approaches, and therapeutic interventions, for potentially fatal or disabling conditions.

Two kinds of condition qualify. Those already identified through ne

Development of novel screening approaches and therapeutic interventions for potentially fatal or disabling conditions identified through newborn screening, and for high priority genetic conditions where screening is not currently recommended but infants would significantly benefit from early identification and treatment. Clinical trials are optional.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.16 Nov 2027
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.
Funding pooliThe total budget available across all awards in this round.$200K

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Last verified: 25 Aug 2026Funder reference: PAR-25-266Source: www.grants.gov