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NIH Phase 1 Exploratory/Developmental Grant (R61)

Mind and Body Interventions to Restore Whole Person Health via Emotional Well-Being Mechanisms

Funds mechanistic trials testing how mind-body practices change emotional well-being, in two gated phases.

OpenNational Institutes of HealthUnited States

Mind-body practices like mindfulness, yoga, acupuncture, and massage are widely used and rarely explained. This notice funds finding the mechanism behind them, not just whether people feel better.

What is asked for is mechanistic research: how these psychological or physical interventions affect the mechanisms of emotional well-being, and how those mechanisms relate to a broader measure the notic…

Mechanistic clinical trials, phased across a feasibility stage and a full-scale stage, testing how mind and body interventions β€” psychological or physical β€” affect mechanisms of emotional well-being and their relationship to the Whole Person Health Index. A clinical trial is required.

CycleiHow often this grant runs β€” e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.7 Jun 2028
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.β€”
Award typeiThe form of funding β€” grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.β€”
Funding pooliThe total budget available across all awards in this round.β€”

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Last verified: 25 Aug 2026Funder reference: PAR-25-449Source: www.grants.gov