Systematic Testing of Radionuclides in Preclinical Experiments (STRIPE)
Funds preclinical research on how radiation from cancer radiopharmaceuticals affects tumors and normal tissue, as a short or a long project.
Radiopharmaceutical therapy treats cancer with radiation delivered by a targeting molecule, and understanding how that radiation actually affects tissue — tumor and healthy alike — is what decides whether the next generation of these treatments works better or just differently. This notice funds that understanding at the preclinical stage.
The named goal is mechanistic: how different forms of rad…
Preclinical cancer-biology research on the biological effects of radionuclide-emitted radiation used in radiopharmaceutical therapy — how it affects normal tissue, tumor cells and the tumor microenvironment — integrating cancer biology, radiation biology, radiochemistry, imaging, dosimetry and preclinical modeling, as either an exploratory/developmental project of up to 2 years or a research project of 4 to 5 years.
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