GREGoRi Innovation Projects
Funds a genuinely new experimental or computational approach to finding the cause of a rare genetic disorder, where the current state of the art falls short.
Roughly half of people with a suspected rare genetic disorder finish the standard diagnostic process without an answer. This notice funds attempts to change that, and it says outright that it wants highly innovative work.
The programme it belongs to is trying to shift the whole approach — the tools, the molecular technologies and the analytical methods used to identify the causal gene or variant …
Development and testing of highly innovative experimental or computational approaches to rare-disease diagnosis, with potential to make transformative improvements over the current state of the art in identifying the causal gene or variant underlying rare genetic disorders. Clinical trials are optional.
Sign up free to see the funding breakdown
Sign up free to see the industries in scope
Sign up free to see the full eligibility
Sign up free to see how to apply
Sign up free to see what you submit
Sign up free to see how they score you
Sign up free to see the timeline
Sign up free to see where teams trip up
Guides for this application
All guides →NIH Biosketch Guide: Format, SciENcv Steps, and Examples
Learn what an NIH biosketch is, how the format works, what to prepare for SciENcv, and how startup teams should avoid common biosketch mistakes.
Write proposalHow to Write a Specific Aims Page
Learn how to write a specific aims page for NIH, SBIR-adjacent, and translational R&D grants, with structure, reviewer logic, examples, and common mistakes.
Where to applyGrants for Biotech Startups: NIH, NSF, SBIR/STTR, and Non-Dilutive Funding
A practical guide to grants for biotech startups, including NIH SBIR/STTR, NSF, translational funding, evidence, regulatory readiness, and budgets.
Write proposalHow to Write a Grant Proposal Reviewers Can Score
Learn how to write a grant proposal around reviewer criteria, evidence, work packages, budget logic, and commercialization for deeptech and R&D funding.
More from NIH
All grants from this funder →Nutrition Obesity Research Centers (NORCs)
🇺🇸NIH · United States
Funds shared research cores, pilot funding and a catalyst programme where a substantial nutrition or obesity research effort already exists.
Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults
🇺🇸NIH · United States
Funds a pilot trial of a behavioural sleep intervention for adolescents and young adults who have a mental health disorder or are at risk of one.
GREGoRi Data Coordination and Outreach Center
🇺🇸NIH · United States
Funds the one centre that coordinates a rare-disease genomics programme and gets its protocols, data and tools out to everybody else.
GREGoRi Technology Integration Center
🇺🇸NIH · United States
Funds the centre that turns new molecular methods for rare-disease diagnosis into standards, best practices and a benchmarking dataset.
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases
🇺🇸NIH · United States
Funds studies that watch patients rather than treat them, in bone, joint, rheumatic and skin disease. No intervention allowed.
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61)
🇺🇸NIH · United States
Funds early-stage clinical trials in arthritis, musculoskeletal and skin disease. A trial is compulsory.
Similar grants
Browse the directory →
DARPA SBIR Phase I
🇺🇸DARPA · United States
Funds United States small businesses validating high-risk defense science concepts for practical technical development.
Moonshot R&D Program — Open PM and Project-Team
🇯🇵CSTI Japan · Japan
Funds disruptive Japan-wide missions in science, society, and advanced technology.
ASPIRE Reduction-to-Practice (Seed)
🇺🇸NCATS · United States
Supports translational chemistry and automation platform development through university-linked partnerships.
ARPA-H Initiatives & Sprints
🇺🇸ARPA-H · United States
Runs fast-turnaround health technology opportunities in United States for high-potential exploratory science and engineering.
SIP Phase 3 — Active Consortia Participation
🇯🇵CSTI Japan · Japan
Funds cross-ministerial Japanese innovation across energy, health, and robotics to strengthen real-world implementation.
ARPA-H Program ISOs (topic-specific)
🇺🇸ARPA-H · United States
Funds United States health initiatives through topic-focused pathways across multiple mission areas and agencies.