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NIH Investigator-Focused Award (R35)

Investigator-Focused Award

Funds an established investigator's whole direction of research inside one NIH institute, instead of a single defined project.

ScheduledNational Institutes of HealthUnited States

Most NIH grants pay for one project with a defined endpoint. This one pays for a scientist's whole direction of travel instead.

What it funds is an investigator's program of research within the mission of a single NIH institute or center, at any career stage, including early-stage investigators. There is no pre-defined project with specific aims to write around โ€” the case is for the person and thโ€ฆ

A single National Institutes of Health institute or center's standing award supporting an established investigator's whole program of research, at any career stage, rather than one pre-defined project with specific aims, so long as the work stays inside that institute's mission.

CycleiHow often this grant runs - e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.4 Oct 2027
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.-
Award typeiThe form of funding - grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.-
Funding pooliThe total budget available across all awards in this round.-

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Guides for this application

All guides โ†’
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Open

Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults

๐Ÿ‡บ๐Ÿ‡ธNIH ยท United States

Funds a pilot trial of a behavioural sleep intervention for adolescents and young adults who have a mental health disorder or are at risk of one.

Oct'26
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Open

GREGoRi Data Coordination and Outreach Center

๐Ÿ‡บ๐Ÿ‡ธNIH ยท United States

Funds the one centre that coordinates a rare-disease genomics programme and gets its protocols, data and tools out to everybody else.

BiotechAI
$1.3MOct'26
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Open

GREGoRi Innovation Projects

NIH ยท United States

Funds a genuinely new experimental or computational approach to finding the cause of a rare genetic disorder, where the current state of the art falls short.

BiotechAI
$3 โ€“ $500KOct'26
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Open

GREGoRi Technology Integration Center

๐Ÿ‡บ๐Ÿ‡ธNIH ยท United States

Funds the centre that turns new molecular methods for rare-disease diagnosis into standards, best practices and a benchmarking dataset.

BiotechAI
$2.3MOct'26
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Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases

๐Ÿ‡บ๐Ÿ‡ธNIH ยท United States

Funds studies that watch patients rather than treat them, in bone, joint, rheumatic and skin disease. No intervention allowed.

Medtech
Nov'26
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Open

Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61)

๐Ÿ‡บ๐Ÿ‡ธNIH ยท United States

Funds early-stage clinical trials in arthritis, musculoskeletal and skin disease. A trial is compulsory.

MedtechBiotech
Nov'26
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Open

MRA Young Investigator Award

๐Ÿ‡บ๐Ÿ‡ธMRA ยท United States

Supports early-career melanoma researchers through fellowships and grants that launch independent research direction.

BiotechMedtech
$255KNov'26
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Open

DoW Vision, Investigator-Initiated Research Award

๐Ÿ‡บ๐Ÿ‡ธMRDC / CDMRP ยท United States

Funds basic-through-early-translational research on service-connected eye injury or visual dysfunction โ€” clinical trials are not part of this one.

Biotech
Nov'26
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Open

DoW Parkinson's, Investigator-Initiated Research Award

๐Ÿ‡บ๐Ÿ‡ธMRDC / CDMRP ยท United States

Funds rigorous Parkinson's disease research for investigators at any career stage, with an optional second PI and clinical trials allowed.

Biotech
Nov'26
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Open

DoW Parkinson's, Early Investigator Research Award

๐Ÿ‡บ๐Ÿ‡ธMRDC / CDMRP ยท United States

Funds early-career Parkinson's research, with a required mentor at the fellow level and none needed at the independent level.

Biotech
Nov'26
Army Medical Research and Development Command logo
Open

DoW Bone Marrow Failure, Investigator-Initiated Research Award

๐Ÿ‡บ๐Ÿ‡ธMRDC / CDMRP ยท United States

Funds mature bone marrow failure research, including drug-development groundwork, but not a clinical trial itself.

Biotech
Nov'26
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Open

DoW Toxic Exposures Investigator Initiated Research Award

๐Ÿ‡บ๐Ÿ‡ธMRDC / CDMRP ยท United States

Funds basic-through-translational research on diseases linked to military-related toxic exposure, at almost any research stage short of a new clinical trial.

Biotech
Nov'26