Experimental medicine: invited stage two application
Funding for human experimental medicine projects testing mechanistic hypotheses.
This funding supports academically led experimental medicine projects conducted in humans. Projects must be based around a clearly articulated gap in understanding of human pathophysiology and have a clear path to clinical impact.
Applications must involve an experimental intervention or challenge in humans, with safety profiles established, designed to validate a mechanistic hypothesis. Challeng…
In scope are academically led experimental medicine projects conducted in humans, based around a clearly articulated gap in understanding of human pathophysiology and a clear path to clinical impact. Applications must involve an experimental intervention or challenge in humans, with safety profiles established, designed to validate a mechanistic hypothesis. Out of scope are biomarker discovery, pre-clinical model development and validation, development and evaluation of novel therapeutics, diagnostics or devices, high-throughput screening approaches to target validation, late-phase clinical efficacy trials, and observational studies involving no experimental challenge.
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