NIH Research Project Grant
Funds a defined research project in the investigator's own area of expertise, through the announcement most NIH institutes keep permanently open.
This is the widest door in United States biomedical funding. Most institutes keep it open permanently rather than publishing their own announcement for ordinary research, and most of the research project money NIH awards comes through it or its siblings.
What it supports is described in the same words the mechanism itself uses: a discrete, specified, circumscribed project, in an area representing…
Discrete, specified, circumscribed research projects in areas representing the investigator's own interests and competencies, relating to the programmatic interests of one or more participating National Institutes of Health institutes and centres. Clinical trials are not accepted under this version.
Sign up free to see the funding breakdown
Sign up free to see the industries in scope
Sign up free to see the full eligibility
Sign up free to see how to apply
Sign up free to see what you submit
Sign up free to see how they score you
Sign up free to see the timeline
Sign up free to see where teams trip up
Guides for this application
All guides →NIH Biosketch Guide: Format, SciENcv Steps, and Examples
Learn what an NIH biosketch is, how the format works, what to prepare for SciENcv, and how startup teams should avoid common biosketch mistakes.
Write proposalHow to Write a Specific Aims Page
Learn how to write a specific aims page for NIH, SBIR-adjacent, and translational R&D grants, with structure, reviewer logic, examples, and common mistakes.
Where to applyGrants for Biotech Startups: NIH, NSF, SBIR/STTR, and Non-Dilutive Funding
A practical guide to grants for biotech startups, including NIH SBIR/STTR, NSF, translational funding, evidence, regulatory readiness, and budgets.
Write proposalHow to Write a Grant Proposal Reviewers Can Score
Learn how to write a grant proposal around reviewer criteria, evidence, work packages, budget logic, and commercialization for deeptech and R&D funding.
More from NIH
All grants from this funder →GREGoRi Data Coordination and Outreach Center
🇺🇸NIH · United States
Funds the one centre that coordinates a rare-disease genomics programme and gets its protocols, data and tools out to everybody else.
GREGoRi Innovation Projects
NIH · United States
Funds a genuinely new experimental or computational approach to finding the cause of a rare genetic disorder, where the current state of the art falls short.
GREGoRi Technology Integration Center
🇺🇸NIH · United States
Funds the centre that turns new molecular methods for rare-disease diagnosis into standards, best practices and a benchmarking dataset.
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases
🇺🇸NIH · United States
Funds studies that watch patients rather than treat them, in bone, joint, rheumatic and skin disease. No intervention allowed.
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61)
🇺🇸NIH · United States
Funds early-stage clinical trials in arthritis, musculoskeletal and skin disease. A trial is compulsory.
Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01)
NIH · United States
Funds theory and method development on how genetic and non-genetic factors together produce variation in complex traits, tested against large existing datasets.
Similar grants
Browse the directory →NICHD R01 Research Project Grant
🇺🇸NICHD · United States
Supports investigator-led biomedical studies across the NICHD portfolio in the United States.
NIDCD R01 Research Project Grant
🇺🇸NIDCD · United States
Funds investigator-led research on hearing, balance, taste, smell, voice, speech, and language through major grants.
NIEHS R01 Research Project Grant
🇺🇸NIEHS · United States
Supports environmental health research grants at United States universities through broad investigator initiatives.
NEI R01 Research Project Grant
🇺🇸NEI · United States
Funds investigator-led basic and clinical vision science at research institutions across the United States.
NSTC Research Project Grant — Seed
🇹🇼NSTC Taiwan · Taiwan
Funds Taiwanese biomedical researchers through general project support for life science discovery.
Project Grant
🇨🇦CIHR (Canadian Institutes of H · Canada
Funds flagship Canadian health investigator grants for biomedical research to strengthen real-world implementation.