Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery
Funds building animal and tissue models that behave enough like a real neurological disease to test drugs against.
Drug discovery for neurological disease keeps failing at the same point: a compound works in the model and not in the patient, because the model never really reproduced the disease.
This route funds fixing the model. It pays for developing and validating animal models and human or animal tissue systems outside the body that recapitulate the phenotypic and physiologic characteristics of a defined …
Developing and validating animal models and ex vivo human or animal tissue systems that recapitulate the phenotype and physiology of a defined neurological or neuromuscular disorder, to improve the translational relevance of neurotherapeutic discovery. No clinical trial.
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