Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R21)
Funds short, exploratory work on what causes agitation, apathy and psychosis in dementia — and what could be targeted to stop it.
Agitation, apathy, depression, psychosis — the neuropsychiatric symptoms of dementia are often what makes it unmanageable at home, and they are much less well understood than the memory loss.
This notice funds studies of the mechanisms behind them in people with Alzheimer's disease or a related dementia. NIH wants both halves of the picture: the biobehavioural pathways and the neurobiological one…
Mechanisms behind neuropsychiatric symptoms in people with Alzheimer's disease or Alzheimer's disease-related dementias, covering both biobehavioural and neurobiological pathways, and the novel therapeutic targets those mechanisms suggest for treating and preventing the symptoms.
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