National Institutes of Health logo
NIH Phase 1 Exploratory/Developmental Grant (R61)

Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33)

Funds two years establishing that a psychosocial intervention hits its target, then three replicating it and linking it to clinical change.

The phased version of the institute's psychosocial development notice, and it buys the whole argument rather than half of it.

The interventions are psychosocial — therapeutic and preventive — for mental disorders. The stated purpose is speeding the translation of emerging basic, behavioural, cognitive, affective and neuropsychological science into interventions people can be given.

The first pha

Phased development of psychosocial therapeutic and preventive interventions for mental disorders: up to two years evaluating target engagement and establishing intervention parameters, then up to three years replicating target engagement from prior studies and testing its association with change in clinical outcomes, translating basic, behavioural, cognitive, affective and neuropsychological science. A clinical trial is required.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.15 Oct 2027
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.
Funding pooliThe total budget available across all awards in this round.

Sign up free to see the funding breakdown

Sign up free to see the industries in scope

Sign up free to see the full eligibility

Sign up free to see how to apply

Sign up free to see what you submit

Sign up free to see how they score you

Sign up free to see the timeline

Sign up free to see where teams trip up

Last verified: 25 Aug 2026Funder reference: PAR-25-182Source: www.grants.gov