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NIH Exploratory/Developmental Research Grant

Investigator Initiated Innovation in Computational Genomics and Data Science (R21)

Funds the exploratory version of the same computational genomics work — new methods, early tools, or hardening software the field depends on.

The exploratory twin of the National Human Genome Research Institute's computational genomics notice. Same scope, smaller mechanism, shorter horizon.

The field is computational genomics, data science, statistics and bioinformatics, relevant to basic or clinical genomic science and broadly applicable to human health and disease.

The same three kinds of work are supported: innovative analytical me

Exploratory research in computational genomics, data science, statistics and bioinformatics for basic or clinical genomic science, covering innovative analytical methodologies, early-stage development of tools and software, and refinement or hardening of high-value existing software, enabling for genomics and generalisable across diseases and biological systems. Every application must address scaling to larger datasets. Clinical trials are not allowed.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.7 Sept 2027
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.
Funding pooliThe total budget available across all awards in this round.

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Last verified: 25 Aug 2026Funder reference: PAR-25-229Source: www.grants.gov