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NIH Investigator-Focused Award (R35)

Maximizing Investigators' Research Award (MIRA)

Funds a single NIGMS investigator's whole research program with one grant, instead of juggling several project-specific awards.

OpenNational Institutes of HealthUnited States

Applying for grant after grant, one research aim at a time, eats the hours a scientist could spend doing the research. This award replaces that pattern with one grant covering an investigator's whole NIGMS-relevant program instead.

Five goals are named directly: steadier funding so investigators can take on ambitious projects; freedom to follow a new direction as the science moves, rather than stโ€ฆ

A single R35 grant replacing multiple NIGMS project grants for one investigator's research program, aimed at stabilizing funding, giving freedom to follow new directions without being bound to aims proposed in advance, spreading funding more widely, and cutting the administrative load of managing several awards โ€” open to eligible NIGMS-funded investigators and to New Investigators, with renewal open to current MIRA holders.

CycleiHow often this grant runs - e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.26 May 2028
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.-
Award typeiThe form of funding - grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.-
Funding pooliThe total budget available across all awards in this round.-

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Guides for this application

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Between cycles

Nutrition Obesity Research Centers (NORCs)

๐Ÿ‡บ๐Ÿ‡ธNIH ยท United States

Funds shared research cores, pilot funding and a catalyst programme where a substantial nutrition or obesity research effort already exists.

$750K
National Institutes of Health logo
Open

Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults

๐Ÿ‡บ๐Ÿ‡ธNIH ยท United States

Funds a pilot trial of a behavioural sleep intervention for adolescents and young adults who have a mental health disorder or are at risk of one.

Oct'26
National Institutes of Health logo
Open

GREGoRi Data Coordination and Outreach Center

๐Ÿ‡บ๐Ÿ‡ธNIH ยท United States

Funds the one centre that coordinates a rare-disease genomics programme and gets its protocols, data and tools out to everybody else.

BiotechAI
$1.3MOct'26
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Open

GREGoRi Innovation Projects

NIH ยท United States

Funds a genuinely new experimental or computational approach to finding the cause of a rare genetic disorder, where the current state of the art falls short.

BiotechAI
$3 โ€“ $500KOct'26
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Open

GREGoRi Technology Integration Center

๐Ÿ‡บ๐Ÿ‡ธNIH ยท United States

Funds the centre that turns new molecular methods for rare-disease diagnosis into standards, best practices and a benchmarking dataset.

BiotechAI
$2.3MOct'26
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Open

Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases

๐Ÿ‡บ๐Ÿ‡ธNIH ยท United States

Funds studies that watch patients rather than treat them, in bone, joint, rheumatic and skin disease. No intervention allowed.

Medtech
Nov'26
Army Medical Research and Development Command logo
Open

DoW Vision, Investigator-Initiated Research Award

๐Ÿ‡บ๐Ÿ‡ธMRDC / CDMRP ยท United States

Funds basic-through-early-translational research on service-connected eye injury or visual dysfunction โ€” clinical trials are not part of this one.

Biotech
Nov'26
Army Medical Research and Development Command logo
Open

DoW Parkinson's, Early Investigator Research Award

๐Ÿ‡บ๐Ÿ‡ธMRDC / CDMRP ยท United States

Funds early-career Parkinson's research, with a required mentor at the fellow level and none needed at the independent level.

Biotech
Nov'26
Melanoma Research Alliance logo
Open

MRA Young Investigator Award

๐Ÿ‡บ๐Ÿ‡ธMRA ยท United States

Supports early-career melanoma researchers through fellowships and grants that launch independent research direction.

BiotechMedtech
$255KNov'26
Army Medical Research and Development Command logo
Open

DoW Bone Marrow Failure, Investigator-Initiated Research Award

๐Ÿ‡บ๐Ÿ‡ธMRDC / CDMRP ยท United States

Funds mature bone marrow failure research, including drug-development groundwork, but not a clinical trial itself.

Biotech
Nov'26
Army Medical Research and Development Command logo
Open

DoW Parkinson's, Investigator-Initiated Research Award

๐Ÿ‡บ๐Ÿ‡ธMRDC / CDMRP ยท United States

Funds rigorous Parkinson's disease research for investigators at any career stage, with an optional second PI and clinical trials allowed.

Biotech
Nov'26
Army Medical Research and Development Command logo
Open

DoW Toxic Exposures Investigator Initiated Research Award

๐Ÿ‡บ๐Ÿ‡ธMRDC / CDMRP ยท United States

Funds basic-through-translational research on diseases linked to military-related toxic exposure, at almost any research stage short of a new clinical trial.

Biotech
Nov'26