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National Institutes of Health

Precision and Systems Biology to Uncover the Link Between Chronic and Infectious Diseases

Funds consortium research using multi-omics and AI on how infections cause chronic illness, and how chronic illness worsens infections.

An infection can leave someone with a health problem that lasts for years after the infection itself is gone, and a long-term illness can make someone more vulnerable to the next infection. NIAID wants both directions of that relationship mapped, not just one.

The research is multidisciplinary and consortium-based, applying precision systems biology to uncover links among chronic illness, infecti

Multidisciplinary, consortium-based precision systems biology research uncovering pathways between chronic illness, infectious disease and the microbiome, using multi-omics, computational modelling, artificial intelligence, organoid-based validation, real-world data integration and digital health records, applied to longitudinal patient cohorts and biobank data to analyse genetic, environmental and lifestyle factors in disease progression and host-pathogen interaction.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.One-off
Next deadlineiThe next date applications are due. Rolling means you can apply any time.22 Jan 2027
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Cooperative agreement
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.
Funding pooliThe total budget available across all awards in this round.$17.5M

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Last verified: 25 Aug 2026Funder reference: RFA-AI-28-014Source: www.grants.gov