National Institutes of Health logo
NIH Exploratory/Developmental Grants Phase II (R33)

Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research

Funds the development and hard technical validation that turns a working cancer research technology into one other laboratories will actually adopt.

The second rung of the National Cancer Institute's technology programme, for teams whose method already works and now has to be made trustworthy.

The entry condition is specific: the major feasibility gaps for the technology or methodology must already have been overcome, and preliminary data has to show it. What remains is further development and rigorous technical validation — the work that per

Further development and rigorous technical validation of emerging technologies for molecular or cellular characterisation of cancer or for biospecimen handling and quality control, where major feasibility gaps have already been overcome with supporting preliminary data, aimed at adoption by the research community across cancer biology, early detection, diagnosis, treatment, control and epidemiology. Clinical trials are not allowed.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Annual
Next deadlineiThe next date applications are due. Rolling means you can apply any time.10 Nov 2026
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.
Funding pooliThe total budget available across all awards in this round.$5.9M

Sign up free to see the funding breakdown

Sign up free to see the industries in scope

Sign up free to see the full eligibility

Sign up free to see how to apply

Sign up free to see what you submit

Sign up free to see how they score you

Sign up free to see the timeline

Sign up free to see where teams trip up

Last verified: 25 Aug 2026Funder reference: RFA-CA-27-002Source: www.grants.gov