NIH Blueprint Initiative: Tools for Germline Gene Editing in the Nervous System
Funds developing and validating gene-editing tools in animal and other model systems used to study the human brain.
Some of the models neuroscience needs to study human brain disease do not exist yet, or exist only in animals whose genomes have not caught up with the questions researchers want to ask of them.
This funds developing, optimising, validating and applying germline and somatic transgenic and gene-editing approaches in experimental systems that model human brain anatomy, circuitry, cognition, behavio…
Developing, optimising, validating and applying germline and somatic transgenic and gene-editing approaches in experimental systems — including non-human-primate and other model systems combined with New Approach Methodologies — that model human brain anatomy, circuitry, cognition, behaviour and lifespan, justified against a specific neuroscience question rather than model convenience.
Sign up free to see the funding breakdown
Sign up free to see the industries in scope
Sign up free to see the full eligibility
Sign up free to see how to apply
Sign up free to see what you submit
Sign up free to see how they score you
Sign up free to see the timeline
Sign up free to see where teams trip up
Guides for this application
All guides →NIH Biosketch Guide: Format, SciENcv Steps, and Examples
Learn what an NIH biosketch is, how the format works, what to prepare for SciENcv, and how startup teams should avoid common biosketch mistakes.
Write proposalHow to Write a Specific Aims Page
Learn how to write a specific aims page for NIH, SBIR-adjacent, and translational R&D grants, with structure, reviewer logic, examples, and common mistakes.
Where to applyGrants for Biotech Startups: NIH, NSF, SBIR/STTR, and Non-Dilutive Funding
A practical guide to grants for biotech startups, including NIH SBIR/STTR, NSF, translational funding, evidence, regulatory readiness, and budgets.
DocumentsGrant Work Plan Template: Work Packages, Gantt, Milestones, and Risks
Use this grant work plan template to structure work packages, tasks, owners, deliverables, Gantt timing, dependencies, and risk registers.
More from NIH
All grants from this funder →GREGoRi Data Coordination and Outreach Center
🇺🇸NIH · United States
Funds the one centre that coordinates a rare-disease genomics programme and gets its protocols, data and tools out to everybody else.
GREGoRi Innovation Projects
NIH · United States
Funds a genuinely new experimental or computational approach to finding the cause of a rare genetic disorder, where the current state of the art falls short.
GREGoRi Technology Integration Center
🇺🇸NIH · United States
Funds the centre that turns new molecular methods for rare-disease diagnosis into standards, best practices and a benchmarking dataset.
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases
🇺🇸NIH · United States
Funds studies that watch patients rather than treat them, in bone, joint, rheumatic and skin disease. No intervention allowed.
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61)
🇺🇸NIH · United States
Funds early-stage clinical trials in arthritis, musculoskeletal and skin disease. A trial is compulsory.
Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01)
NIH · United States
Funds theory and method development on how genetic and non-genetic factors together produce variation in complex traits, tested against large existing datasets.
Similar grants
Browse the directory →
ARPA-H SBIR/STTR
🇺🇸ARPA-H · United States
Funds United States small businesses bridging health and neuroscience technologies from feasibility into advanced development.
DTRA C-WMD Basic Research BAA
🇺🇸DTRA · United States
Supports fundamental and early-stage scientific research that protects against chemical, biological, radiological, and nuclear risks.
ARPA-H Initiatives & Sprints
🇺🇸ARPA-H · United States
Runs fast-turnaround health technology opportunities in United States for high-potential exploratory science and engineering.
ARPA-H Program ISOs (topic-specific)
🇺🇸ARPA-H · United States
Funds United States health initiatives through topic-focused pathways across multiple mission areas and agencies.
ARPA-H Mission Office ISOs
🇺🇸ARPA-H · United States
Supports United States mission teams with boundary-pushing health initiatives beyond existing programme limits.
Emerging Infections Network - Research for Preventing, Detecting, and Managing Travel-associated Infectious Diseases
🇺🇸CDC · United States
Funds surveillance and research networks that detect, diagnose and track infectious diseases among international travelers.