BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain
Funds exploratory human studies that record and stimulate neurons directly, using brain access that invasive procedures already create.
Getting direct electrical access to living human brain tissue almost always requires a medical reason to be there in the first place. This notice funds using that access, once it exists, to ask fundamental neuroscience questions.
The scope is exploratory research using invasive surgical procedures that already give direct, precisely localised access to record and stimulate neuronal activity in th…
Exploratory and planning research using invasive surgical procedures that provide direct, precisely localised access to record and stimulate neuronal activity in the human brain, to understand how single-cell and neuronal-ensemble activity produces internal states and observable behaviour — feasibility work laying the groundwork for a later full research grant using the same approach, with participation in a shared NIH consortium working group built into the award.
Sign up free to see the funding breakdown
Sign up free to see the industries in scope
Sign up free to see the full eligibility
Sign up free to see how to apply
Sign up free to see what you submit
Sign up free to see how they score you
Sign up free to see the timeline
Sign up free to see where teams trip up
Guides for this application
All guides →NIH Biosketch Guide: Format, SciENcv Steps, and Examples
Learn what an NIH biosketch is, how the format works, what to prepare for SciENcv, and how startup teams should avoid common biosketch mistakes.
Write proposalHow to Write a Specific Aims Page
Learn how to write a specific aims page for NIH, SBIR-adjacent, and translational R&D grants, with structure, reviewer logic, examples, and common mistakes.
Write proposalHow to Write a Grant Proposal Reviewers Can Score
Learn how to write a grant proposal around reviewer criteria, evidence, work packages, budget logic, and commercialization for deeptech and R&D funding.
DocumentsGrant Work Plan Template: Work Packages, Gantt, Milestones, and Risks
Use this grant work plan template to structure work packages, tasks, owners, deliverables, Gantt timing, dependencies, and risk registers.
More from NIH
All grants from this funder →Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults
🇺🇸NIH · United States
Funds a pilot trial of a behavioural sleep intervention for adolescents and young adults who have a mental health disorder or are at risk of one.
GREGoRi Data Coordination and Outreach Center
🇺🇸NIH · United States
Funds the one centre that coordinates a rare-disease genomics programme and gets its protocols, data and tools out to everybody else.
GREGoRi Innovation Projects
NIH · United States
Funds a genuinely new experimental or computational approach to finding the cause of a rare genetic disorder, where the current state of the art falls short.
GREGoRi Technology Integration Center
🇺🇸NIH · United States
Funds the centre that turns new molecular methods for rare-disease diagnosis into standards, best practices and a benchmarking dataset.
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases
🇺🇸NIH · United States
Funds studies that watch patients rather than treat them, in bone, joint, rheumatic and skin disease. No intervention allowed.
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61)
🇺🇸NIH · United States
Funds early-stage clinical trials in arthritis, musculoskeletal and skin disease. A trial is compulsory.
Similar grants
Browse the directory →
Making America Healthy Again — Dementia Disparities (OMH) — Seed
🇺🇸HHS · United States
Supports community-based teams reducing dementia and brain-health disparities in underserved groups through social-determinant-focused strategies.
US-Ireland R&D Partnership
🇮🇪HRB (Health Research Board Ire · Ireland
Connects United States and United Kingdom researchers through joint biomedical innovation grants.
NEI STTR Phase I — Feasibility
🇺🇸NEI · United States
Funds small business and research-partner teams on feasibility vision tools for future commercialization.
NEI SBIR Phase I — Feasibility
🇺🇸NEI · United States
Supports United States. small businesses testing vision concepts through feasibility-focused grants.
NCATS STTR Phase I
🇺🇸NCATS · United States
Funds U.S. small businesses and their nonprofit research partners to conduct feasibility studies on translational science innovations toward commercialization.
Parkinson's Foundation Stanley Fahn Junior Faculty Award
🇺🇸Parkinson's Foundation · United States
Funds early-career Parkinson's disease researchers at United States and Canada institutions through independent investigator support.