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NIH Research Project Cooperative Agreement (U01)

Optimal Treatment Strategies for use of Anti-Obesity Medications (AOMs) in Children and Adolescents Clinical Centers

Funds a clinical centre inside a consortium testing how to use anti-obesity medication in children without harming their growth or mental health.

ClosedNational Institutes of HealthUnited States

Anti-obesity medication works in children. What nobody has settled is how to use it โ€” at what age to start, how fast to let weight come off, for how long, and what has to run alongside it so a child still grows up healthy. This consortium is being built to answer that.

This notice funds the clinical centres. A separate companion notice funds the coordinating centre they all report into.

The treaโ€ฆ

Clinical centre awards in a consortium testing anti-obesity medication treatment strategies in youth โ€” timing of initiation, rate and amount of weight loss, drug class, dose, frequency, duration and adjunct lifestyle therapy โ€” protecting growth, nutrition, mental health and quality of life, with shared protocols, measures, central laboratory and analysis across the consortium. A clinical trial is required.

CycleiHow often this grant runs - e.g. annually, on a rolling basis, or a one-off call.One-off
Next deadlineiThe next date applications are due. Rolling means you can apply any time.-
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.-
Award typeiThe form of funding - grant, equity, loan, tax credit, etc.Cooperative agreement
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.-
Funding pooliThe total budget available across all awards in this round.$3M

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Guides for this application

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Between cycles

Nutrition Obesity Research Centers (NORCs)

๐Ÿ‡บ๐Ÿ‡ธNIH ยท United States

Funds shared research cores, pilot funding and a catalyst programme where a substantial nutrition or obesity research effort already exists.

$750K
National Institutes of Health logo
Open

Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults

๐Ÿ‡บ๐Ÿ‡ธNIH ยท United States

Funds a pilot trial of a behavioural sleep intervention for adolescents and young adults who have a mental health disorder or are at risk of one.

Oct'26
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Open

GREGoRi Data Coordination and Outreach Center

๐Ÿ‡บ๐Ÿ‡ธNIH ยท United States

Funds the one centre that coordinates a rare-disease genomics programme and gets its protocols, data and tools out to everybody else.

BiotechAI
$1.3MOct'26
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Open

GREGoRi Innovation Projects

NIH ยท United States

Funds a genuinely new experimental or computational approach to finding the cause of a rare genetic disorder, where the current state of the art falls short.

BiotechAI
$3 โ€“ $500KOct'26
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Open

GREGoRi Technology Integration Center

๐Ÿ‡บ๐Ÿ‡ธNIH ยท United States

Funds the centre that turns new molecular methods for rare-disease diagnosis into standards, best practices and a benchmarking dataset.

BiotechAI
$2.3MOct'26
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Open

Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases

๐Ÿ‡บ๐Ÿ‡ธNIH ยท United States

Funds studies that watch patients rather than treat them, in bone, joint, rheumatic and skin disease. No intervention allowed.

Medtech
Nov'26