National Institutes of Health logo
NIH Research Demonstration and Dissemination Project (R18)

BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS

Funds a novel recording or modulation technology for the human central nervous system from proof of concept up to readiness for first-in-human studies.

OpenNational Institutes of HealthUnited States

This is the notice that takes a neural interface as far as it can go before it enters a person.

The technologies are for recording from or modulating the human central nervous system, to treat or diagnose its diseases and disorders and to understand it better.

The range funded is stated exactly: from proof of concept up to the stage of readiness for first-in-human studies. That covers the work m…

Translation of novel recording and modulation technologies for the human central nervous system, using electrical, optical, magnetic, acoustic or combined signal modalities, from proof of concept up to readiness for first-in-human studies, for treating or diagnosing central nervous system diseases and disorders and for understanding the human central nervous system. Clinical trials are not allowed.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Annual
Next deadlineiThe next date applications are due. Rolling means you can apply any time.28 Jan 2027
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.—
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.—
Funding pooliThe total budget available across all awards in this round.—

Sign up free to see the funding breakdown

Sign up free to see the industries in scope

Sign up free to see the full eligibility

Sign up free to see how to apply

Sign up free to see what you submit

Sign up free to see how they score you

Sign up free to see the timeline

Sign up free to see where teams trip up

Last verified: 25 Aug 2026Funder reference: RFA-NS-24-031Source: www.grants.gov