BRAIN Initiative: Next-Generation Devices for Recording and Modulation in the Human Central Nervous System
Funds taking a brain recording or stimulation device from prototype through safety testing and an FDA exemption into a first small clinical study.
This is the translational stretch of the BRAIN Initiative's device programme — the part between a device that works in a laboratory and a device that has been used in a person.
The funded activities are named: implementing clinical prototype devices, non-clinical safety and efficacy testing, design verification and validation, obtaining an Investigational Device Exemption for a Significant Risk s…
Translational development of therapeutic and diagnostic devices for disorders of the nervous and neuromuscular systems — clinical prototype implementation, non-clinical safety and efficacy testing, design verification and validation, obtaining an Investigational Device Exemption for a Significant Risk study, and a subsequent small clinical study.
Sign up free to see the funding breakdown
Sign up free to see the industries in scope
Sign up free to see the full eligibility
Sign up free to see how to apply
Sign up free to see what you submit
Sign up free to see how they score you
Sign up free to see the timeline
Sign up free to see where teams trip up
Guides for this application
All guides →NIH Biosketch Guide: Format, SciENcv Steps, and Examples
Learn what an NIH biosketch is, how the format works, what to prepare for SciENcv, and how startup teams should avoid common biosketch mistakes.
Write proposalHow to Write a Specific Aims Page
Learn how to write a specific aims page for NIH, SBIR-adjacent, and translational R&D grants, with structure, reviewer logic, examples, and common mistakes.
Write proposalHow to Write a Grant Proposal Reviewers Can Score
Learn how to write a grant proposal around reviewer criteria, evidence, work packages, budget logic, and commercialization for deeptech and R&D funding.
DocumentsGrant Work Plan Template: Work Packages, Gantt, Milestones, and Risks
Use this grant work plan template to structure work packages, tasks, owners, deliverables, Gantt timing, dependencies, and risk registers.
More from NIH
All grants from this funder →Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults
🇺🇸NIH · United States
Funds a pilot trial of a behavioural sleep intervention for adolescents and young adults who have a mental health disorder or are at risk of one.
GREGoRi Data Coordination and Outreach Center
🇺🇸NIH · United States
Funds the one centre that coordinates a rare-disease genomics programme and gets its protocols, data and tools out to everybody else.
GREGoRi Innovation Projects
NIH · United States
Funds a genuinely new experimental or computational approach to finding the cause of a rare genetic disorder, where the current state of the art falls short.
GREGoRi Technology Integration Center
🇺🇸NIH · United States
Funds the centre that turns new molecular methods for rare-disease diagnosis into standards, best practices and a benchmarking dataset.
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases
🇺🇸NIH · United States
Funds studies that watch patients rather than treat them, in bone, joint, rheumatic and skin disease. No intervention allowed.
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61)
🇺🇸NIH · United States
Funds early-stage clinical trials in arthritis, musculoskeletal and skin disease. A trial is compulsory.
Similar grants
Browse the directory →
Next-Generation Devices for Recording and Modulation in the Human CNS
🇺🇸BRAIN Initiative · United States
Supports the development of next-generation neural devices for human neuroscience applications through collaborative research.
Clinical Studies to Advance Next-Generation Devices for Recording/Modulation in Human CNS
🇺🇸BRAIN Initiative · United States
Funds human clinical studies of next-generation neural devices through research agreements.
NIH Blueprint MedTech Translator
🇺🇸NINDS · United States
Funds translational neurotechnology device development through structured milestones and multi-year collaboration.
Preclinical Proof of Concept for Novel Recording/Modulation Technologies in Human CNS
🇺🇸BRAIN Initiative · United States
Funds preclinical testing for novel neural recording and modulation technologies before clinical transition.
Brain Behavior Quantification and Synchronization — Next Gen Sensor Technology Development
🇺🇸BRAIN Initiative · United States
Supports neural behavior-sensing technology development through translational cooperative projects.
Continuing Human Enabling Enhancing Restoring and Sustaining
🇺🇸AFRL · United States
Funds Air Force human-performance research, but only through the two grant-eligible solicitations sitting beneath this umbrella notice.