Exposomic Contributions to ADRD Pathology and Resilience
Funds research on how toxins, sleep, stress and other everyday exposures mechanistically shape Alzheimer's-related dementia.
Alzheimer's disease-related dementias are not purely genetic, and this notice funds working out how the environment and daily life actually get under the skin to shape them. The factors named are environmental toxins, sleep and circadian rhythms, stress, and the real-world conditions that drive them — light, noise, heat.
What is asked for goes beyond any single factor. Applications are expected t…
Mechanistic research on how neural exposome factors — environmental toxins, sleep and circadian rhythms, stress, and modulating conditions such as light, noise and heat — and their combinations contribute to Alzheimer's disease-related dementia pathology and resilience, across the lifespan. NIH-defined clinical trials are not supported.
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