RNomics Technology Enhancement Centers
Funds centers that take working RNA-analysis technology and push it further, not invent something new from scratch.
A cell runs on more than DNA and protein. The full set of RNA molecules in it — the RNome — carries sequence, chemical modifications, structure, location, and interactions that today's tools only partly capture.
This notice is one of four initiatives under the NIH Common Fund's RNomics program, alongside a transformative-technologies track, a molecular-standards track, and a coordinating center. …
Further development of existing RNA-analysis technologies with demonstrated feasibility, strengthening experimental and computational tools for measuring, mapping and testing the full set of cellular RNA molecules (the RNome), covering end-to-end RNA sequencing and modification mapping, comprehensive analysis of RNA sequence, structure, modification, interactions and function, and molecular tools for RNA manipulation and functional testing.
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