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NIH SBIR

NIH, CDC and FDA Small Business Innovation Research Grant

Funds early feasibility work through late-stage R&D for a US small business turning a health science idea into a marketable product.

OpenNational Institutes of HealthUnited States

A promising piece of health science does not turn itself into a product, and a small company rarely has the budget to make that leap on spec.

This is NIH's standing Small Business Innovation Research door for exactly that gap. It supports feasibility studies first, then the research and development a promising result needs to become a commercial product, across every participating NIH institute a…

Two-phase Small Business Innovation Research funding β€” feasibility studies followed by research and development β€” open to any United States small business concern developing a scientific innovation into a commercial product, across the National Institutes of Health, CDC and FDA missions. Clinical trials are optional.

CycleiHow often this grant runs β€” e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.5 Apr 2027
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.β€”
Award typeiThe form of funding β€” grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.β€”
Funding pooliThe total budget available across all awards in this round.β€”

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Last verified: 25 Aug 2026Funder reference: PA-27-100Source: www.grants.gov