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NIH Research Project Grant

Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants

Funds an addition to an existing NIH grant, to take a cancer biomarker assay from working in the lab to working in the clinic.

The National Cancer Institute funds a great many assays that never leave the laboratory that built them. This route pays to close that gap — but only for people who already hold the grant that produced the assay.

What it funds is adapting and clinically validating molecular, cellular and imaging markers for cancer detection, diagnosis, prognosis, monitoring and predicting response to treatment, p

Adapting and clinically validating molecular, cellular and imaging biomarkers for cancer detection, diagnosis, prognosis, monitoring and prediction of treatment response, and for cancer control and prevention — including acquiring annotated specimens where validation requires them. Early-stage technology development and running clinical trials are both out of scope.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.14 Oct 2026
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.
Funding pooliThe total budget available across all awards in this round.

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Last verified: 25 Aug 2026Funder reference: PAR-24-304Source: www.grants.gov