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NIH Exploratory/Developmental Cooperative Agreement Phase I (UH2)

Assay Validation of High Quality Markers for Clinical Studies in Cancer

Funds two years of analytical validation then three of clinical validation for a cancer biomarker assay that already works on human samples.

OpenNational Institutes of HealthUnited States

The National Cancer Institute funds the validation of molecular, cellular and imaging markers and the assays that measure them — for cancer detection, diagnosis, prognosis, monitoring, and predicting response or resistance to treatment, as well as for prevention and control. Pharmacodynamic markers and markers of toxicity are in scope too.

The entry condition is concrete: applicants should alread…

Analytical and clinical validation of molecular, cellular and imaging biomarker assays for cancer detection, diagnosis, prognosis, monitoring and prediction of response or resistance, plus prevention, control, pharmacodynamic and toxicity markers. Two years analytical, then up to three clinical, including cross-laboratory harmonisation.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.14 Oct 2026
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.—
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Cooperative agreement
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.—
Funding pooliThe total budget available across all awards in this round.—

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Last verified: 25 Aug 2026Funder reference: PAR-25-074Source: www.grants.gov