National Institutes of Health logo
NIH Research Project Grant

Full-Scale Hybrid Effectiveness-Implementation Trials for Mental Health Interventions

Funds a definitive trial of a mental health treatment or service in real community and practice settings, powered to settle the question.

An intervention that works in a research clinic is not the same as one that works in a community mental health centre. This notice funds finding out, and it is the late stage of the institute's trials pipeline.

Two kinds of trial are supported. Effectiveness trials of optimised therapeutic and preventive interventions for use in community and practice settings. And trials evaluating services inte…

Effectiveness trials of optimised therapeutic and preventive mental health interventions for community and practice settings, and trials of patient, provider, organisational or systems-level services interventions improving access, continuity, quality, equity or value of mental health services, adequately powered to definitively answer the primary questions with hypotheses supported by pilot data. A clinical trial is required.

CycleiHow often this grant runs - e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.15 Oct 2027
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.-
Award typeiThe form of funding - grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.-
Funding pooliThe total budget available across all awards in this round.-

Sign up free to see the funding breakdown

Sign up free to see the industries in scope

Sign up free to see the full eligibility

Sign up free to see how to apply

Sign up free to see what you submit

Sign up free to see how they score you

Sign up free to see the timeline

Sign up free to see where teams trip up

Guides for this application

All guides →
Parkinson's Foundation logo
Open

Parkinson's Foundation Impact Awards

Parkinson's Foundation · United States

Funds independent Parkinson's disease investigators pursuing bold, high-risk projects with translational clinical relevance.

BiotechNeurotech+1
$200KMar'27
28DIGITAL (formerly EIT Digital) logo
Open

EIT Digital Open Innovation Factory

28DIGITAL · European Union

Funds European digital startups at TRL 4-5 seeking co-development with industry partners through EIT Digital's open innovation matching platform.

AIBiotech+10
Parkinson's Foundation logo
Open

Parkinson's Foundation Melvin Yahr Clinical Research Award

Parkinson's Foundation · United States

Supports early-career clinicians advancing Parkinson's disease care and research collaborations across emerging regions.

MedtechNeurotech
$50KJan'27
Parkinson's Foundation logo
Open

Parkinson's Foundation Postdoctoral Fellowship — Basic Scientists

Parkinson's Foundation · United States

Supports early Parkinson's disease scientists building translational impact by funding postdoctoral research roles.

BiotechNeurotech+1
$140KFeb'27
NIH BRAIN Initiative logo
Open

Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain

BRAIN Initiative · United States

Funds new methods to study brain cells and circuits with tools for deeper neural research.

NeurotechBiotech+1
Feb'27
FDA — Food and Drug Administration logo
Open

Reissue of RFA-FD-22-001 - Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases

FDA · United States

Funds natural history studies that track how a rare disease unfolds over time, to close data gaps blocking new treatments for it.

Biotech
$600KFeb'28