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NIH Research Project Grant

Full-Scale Hybrid Effectiveness-Implementation Trials for Mental Health Interventions

Funds a definitive trial of a mental health treatment or service in real community and practice settings, powered to settle the question.

An intervention that works in a research clinic is not the same as one that works in a community mental health centre. This notice funds finding out, and it is the late stage of the institute's trials pipeline.

Two kinds of trial are supported. Effectiveness trials of optimised therapeutic and preventive interventions for use in community and practice settings. And trials evaluating services inte

Effectiveness trials of optimised therapeutic and preventive mental health interventions for community and practice settings, and trials of patient, provider, organisational or systems-level services interventions improving access, continuity, quality, equity or value of mental health services, adequately powered to definitively answer the primary questions with hypotheses supported by pilot data. A clinical trial is required.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.15 Oct 2027
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.
Funding pooliThe total budget available across all awards in this round.

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Last verified: 25 Aug 2026Funder reference: PAR-25-177Source: www.grants.gov