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NIH Research Project Grant

Confirmatory Efficacy Clinical Trials of Non-Pharmacological and Pharmacological Interventions for Mental Disorders

Funds a confirmatory efficacy trial of a non-drug treatment or preventive intervention for mental disorders, in adults or children.

Between a promising psychological or behavioural treatment and one anybody can rely on sits a confirmatory efficacy trial. This notice funds it.

The interventions are non-pharmacological therapeutic and preventive approaches for mental disorders, in adults and in children. The condition on which ones qualify is stated: they must address unmet therapeutic needs.

The institute's experimental thera

Confirmatory efficacy trials of non-pharmacological therapeutic and preventive interventions for mental disorders in adults and children addressing unmet therapeutic needs, designed to increase knowledge of the relationship between underlying disease processes and the mechanisms of action through which the intervention produces therapeutic change. A clinical trial is required.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.15 Oct 2027
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.
Funding pooliThe total budget available across all awards in this round.

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Last verified: 25 Aug 2026Funder reference: PAR-25-179Source: www.grants.gov