Small Business Transition Grant for New Entrepreneurs (R41/R42)
Funds a first STTR grant and entrepreneurial mentoring for a scientist who partners with a nonprofit institution and has never led research funding before.
This is the STTR twin of NIH's small-business transition grant, and it differs from its SBIR sibling in two concrete ways: it requires a formal research partnership with a nonprofit institution, and it runs through NIH alone rather than NIH and the CDC together.
It funds Small Business Technology Transfer Phase I applications, and Fast-Track applications combining Phase I and Phase II, for United…
Small Business Technology Transfer Phase I and Fast-Track grant applications for United States small business concerns partnering with a nonprofit research institution, combining research and development funding with entrepreneurial training, mentoring and career development for a first-time principal investigator transitioning into entrepreneurship. A clinical trial is optional.
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Guides for this application
All guides →SBIR/STTR Grants for Deeptech Startups
A practical guide to SBIR and STTR grants for deeptech startups, including agency fit, Phase I and II logic, eligibility, budgets, and review criteria.
DocumentsNIH Biosketch Guide: Format, SciENcv Steps, and Examples
Learn what an NIH biosketch is, how the format works, what to prepare for SciENcv, and how startup teams should avoid common biosketch mistakes.
Write proposalHow to Write a Specific Aims Page
Learn how to write a specific aims page for NIH, SBIR-adjacent, and translational R&D grants, with structure, reviewer logic, examples, and common mistakes.
Where to applyGrants for Biotech Startups: NIH, NSF, SBIR/STTR, and Non-Dilutive Funding
A practical guide to grants for biotech startups, including NIH SBIR/STTR, NSF, translational funding, evidence, regulatory readiness, and budgets.
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