National Institutes of Health logo
NIH Research Project Cooperative Agreement (U01)

Causal Hypotheses on the Oral-Systemic Health Impacts of Human Behaviors among People with Chronic Conditions

Funds research testing causal links between everyday human behaviors and oral-systemic health outcomes in people with chronic conditions.

OpenNational Institutes of HealthUnited States

Behavior drives a lot of health outcomes, and the link between what people do and what happens to their mouths and the rest of their body is still mostly untested as cause and effect. This notice funds studies that try to prove the chain, not just describe it.

What counts as a cause is defined broadly: biological, biopsychosocial, congenital, environmental, interpersonal, neurological, psychologi…

Investigator-initiated research testing causal hypotheses — biological, biopsychosocial, congenital, environmental, interpersonal, neurological, psychological or comorbidity factors, alone or combined — that link human behaviors to oral-systemic health outcomes in people with chronic conditions, including projects that only develop or refine such a hypothesis. A clinical trial is not allowed.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.5 Jul 2029
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.—
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Cooperative agreement
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.—
Funding pooliThe total budget available across all awards in this round.—

Sign up free to see the funding breakdown

Sign up free to see the industries in scope

Sign up free to see the full eligibility

Sign up free to see how to apply

Sign up free to see what you submit

Sign up free to see how they score you

Sign up free to see the timeline

Sign up free to see where teams trip up

Last verified: 25 Aug 2026Funder reference: PAR-27-057Source: www.grants.gov