Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development
Funds small-molecule drug candidates from a lab bench through Phase I testing, with NIH's own chemistry and toxicology experts on call.
An academic lab can often find a promising small molecule, but rarely has the pharmacology, toxicology and manufacturing muscle to get it into a person safely — and that gap is where a lot of good candidates quietly die.
This notice funds crossing it. Small-molecule drug discovery and development work runs in the investigator's own laboratory, with access to NIH-supported subject matter experts a…
Phased cooperative-agreement support for small-molecule drug discovery and development toward clinical testing, run in the investigator's own laboratory with NIH-supported subject matter experts and contract research organizations providing medicinal chemistry, pharmacokinetics, toxicology, formulation and GMP synthesis capacity through Phase I. Biologics are excluded.
Sign up free to see the funding breakdown
Sign up free to see the industries in scope
Sign up free to see the full eligibility
Sign up free to see how to apply
Sign up free to see what you submit
Sign up free to see how they score you
Sign up free to see the timeline
Sign up free to see where teams trip up
Guides for this application
All guides →NIH Biosketch Guide: Format, SciENcv Steps, and Examples
Learn what an NIH biosketch is, how the format works, what to prepare for SciENcv, and how startup teams should avoid common biosketch mistakes.
Write proposalHow to Write a Specific Aims Page
Learn how to write a specific aims page for NIH, SBIR-adjacent, and translational R&D grants, with structure, reviewer logic, examples, and common mistakes.
Where to applyGrants for Biotech Startups: NIH, NSF, SBIR/STTR, and Non-Dilutive Funding
A practical guide to grants for biotech startups, including NIH SBIR/STTR, NSF, translational funding, evidence, regulatory readiness, and budgets.
DocumentsGrant Work Plan Template: Work Packages, Gantt, Milestones, and Risks
Use this grant work plan template to structure work packages, tasks, owners, deliverables, Gantt timing, dependencies, and risk registers.
More from NIH
All grants from this funder →GREGoRi Data Coordination and Outreach Center
🇺🇸NIH · United States
Funds the one centre that coordinates a rare-disease genomics programme and gets its protocols, data and tools out to everybody else.
GREGoRi Innovation Projects
NIH · United States
Funds a genuinely new experimental or computational approach to finding the cause of a rare genetic disorder, where the current state of the art falls short.
GREGoRi Technology Integration Center
🇺🇸NIH · United States
Funds the centre that turns new molecular methods for rare-disease diagnosis into standards, best practices and a benchmarking dataset.
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases
🇺🇸NIH · United States
Funds studies that watch patients rather than treat them, in bone, joint, rheumatic and skin disease. No intervention allowed.
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61)
🇺🇸NIH · United States
Funds early-stage clinical trials in arthritis, musculoskeletal and skin disease. A trial is compulsory.
Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01)
NIH · United States
Funds theory and method development on how genetic and non-genetic factors together produce variation in complex traits, tested against large existing datasets.
Similar grants
Browse the directory →NIA Alzheimer's Drug-Development Program
🇺🇸NIA · United States
Funds collaborative research alliances that accelerate Alzheimer's drug development in the United States.
DoW Joint Warfighter Medical, Military Medical Research and Development Award
🇺🇸MRDC / CDMRP · United States
Funds a continuation phase for medical research that already holds earlier DOD or DOW funding, from preclinical work through clinical trials.
Brain Behavior Quantification and Synchronization — Next Gen Sensor Technology Development
🇺🇸BRAIN Initiative · United States
Supports neural behavior-sensing technology development through translational cooperative projects.
Emerging Infections Network - Research for Preventing, Detecting, and Managing Travel-associated Infectious Diseases
🇺🇸CDC · United States
Funds surveillance and research networks that detect, diagnose and track infectious diseases among international travelers.
DOD Defense Health Agency (DHA) Research & Development FY23-FY27 BROAD AGENCY ANNOUNCEMENT for Extramural Medical Research
🇺🇸MRDC / CDMRP · United States
Funds an unsolicited medical research idea across USAMRDC's whole portfolio, but only after a pre-proposal through eBRAP earns an invitation to submit in full.
Animal and Veterinary Innovation Centers
🇺🇸FDA · United States
Funds academic institutions to become long-term FDA partners researching bird flu, animal genomics and unmet veterinary needs.