NIH Common Fund logo
NIH Director's Transformative Research Award

NIH Director's Transformative Research Award for Individual and Group Science

Funds bold, unconventional biomedical science with no preliminary data required β€” about seven awards from an $8 million pool.

OpenNIH Common FundUnited States

This is NIH's award for the idea that is too strange to survive a normal review. It backs individual scientists or groups proposing bold, unconventional work that could create a new scientific paradigm, establish a genuinely new clinical approach, or produce a transformative technology.

The unusual part is that no preliminary data are required. Most NIH applications live or die on the evidence yo…

Bold, unconventional and high-risk biomedical research in any area β€” basic, translational or clinical β€” where the case rests on the logic of the idea rather than on preliminary data, and where success would create a new scientific paradigm, a new clinical approach, or a transformative technology.

CycleiHow often this grant runs β€” e.g. annually, on a rolling basis, or a one-off call.Annual
Next deadlineiThe next date applications are due. Rolling means you can apply any time.3 Sept 2026
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.β€”
Award typeiThe form of funding β€” grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.β€”
Funding pooliThe total budget available across all awards in this round.$8M

Sign up free to see the funding breakdown

Sign up free to see the industries in scope

Sign up free to see the full eligibility

Sign up free to see how to apply

Sign up free to see what you submit

Sign up free to see how they score you

Sign up free to see the timeline

Sign up free to see where teams trip up

Last verified: 25 Aug 2026Funder reference: RFA-RM-27-003Source: www.grants.gov