Complement-ARIE NAMs Reduction to Practice Challenge
Awards up to $7,000,000 in cash prizes to teams building lab-based alternatives to animal testing.
Phase 1 proposals are scored against five weighted criteria out of 100 points total: Significance/Impact (15), Innovation (10), Team (15), Feasibility and Preliminary Data (25), and Approach (35), after a preliminary screen for eligibility and completeness; a federal Judging Panel then selects winners subject to sign-off from the Award Approving Official, and evaluation results are never shared wi…
This NIH Common Fund challenge, run with FDA and EPA input, is looking for combinatorial 'new approach methodologies' (NAMs) that combine cell/tissue/organoid, computational, and biochemical techniques to complement or replace animal models in biomedical research and regulatory testing. Priority areas include chronic-disease modeling, neurobiological and personalized-medicine models, cross-disease platforms, toxicology and safety testing, and human health protection studies, though solvers aren't limited to these areas.
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