Grants by programme

SBIR and STTR grants

SBIR and STTR are the United States' seed fund for small companies with a technical idea a federal agency wants to see built. Each agency runs its own calls under the same rules, so the openings are scattered across a dozen sites. This page gathers every one the catalogue tracks, open calls first, from the health, science, space, energy and defence agencies down to the state programmes that top up a federal award.

Showing 25-48 of 160 grants

Air Force Research Laboratory logo
Open

AFOSR STTR

🇺🇸AFRL · United States

Funds collaborative basic research pathways for technology transfer from concept through scalable prototypes.

DefenseAerospace+2
$60K – $750K
AFWERX logo
Open

AFWERX Open Topic SBIR/STTR

🇺🇸AFWERX · United States

Offers AFWERX open topic support for United States small businesses with dual use ideas through an always open route.

AerospaceAI+5
$75K – $2M
Defense Health Agency logo
Open

Defense Health Agency SBIR Phase I

🇺🇸DHA · United States

Funds United States defense medical innovators at feasibility stage for life-changing military health technologies.

DefenseMedtech+2
$323K
Defense Health Agency logo
Open

Defense Health Agency SBIR Phase II

🇺🇸DHA · United States

Supports United States defense health teams maturing validated medical technologies toward practical military use.

DefenseMedtech+2
$2.2M
DHS Science and Technology Directorate logo
Open

DHS SBIR Phase II (invite-only)

🇺🇸DHS S&T · United States

Supports small businesses in the United States advancing proven homeland security prototypes in a second-stage federal programme.

CybersecurityDefense+4
$1M – $1.5M
U.S. Department of Defense logo
Open

DoD SBIR/STTR

🇺🇸DoD · United States

Supports small business and non-traditional teams across defense components in a shared topic flow.

AerospaceAI+11
DOE Office of Science — Advanced Scientific Computing Research (ASCR) logo
Open

DOE SBIR/STTR ASCR Topics

🇺🇸DOE ASCR · United States

Offers innovation teams support in advanced computing and hardware-oriented technologies.

AIQuantum+2
$200K – $1.6M
US Department of Education — Institute of Education Sciences logo
Open

ED/IES SBIR Phase II (Standard — Phase I Graduates)

🇺🇸IES · United States

Supports United States education small businesses turning early feasibility into commercially viable offerings.

AIHardware+2
$1M
Pennsylvania Department of Community & Economic Development logo
Open

Innovation Partnership (IPart) SBIR/STTR Proposal Support

🇺🇸PA DCED · United States

Offers Pennsylvania small businesses free proposal reviews, training seminars, and travel support for federal innovation applications.

AIBiotech+6
$1K
Kentucky Cabinet for Economic Development — KY Innovation logo
Open

Kentucky SBIR/STTR Match — Phase I

🇺🇸KY Innovation · United States

Funds Kentucky companies with state matching support for early federally aligned innovation projects.

BiotechMedtech+7
$100K
Kentucky Cabinet for Economic Development — KY Innovation logo
Open

Kentucky SBIR/STTR Match — Phase II

🇺🇸KY Innovation · United States

Funds Kentucky companies with larger state matching support as innovation projects move toward commercialization.

BiotechMedtech+7
$150K
Kentucky Economic Development Finance Authority logo
Open

Kentucky SBIR/STTR Matching Funds

🇺🇸KEDFA · United States

Supports Kentucky high-technology companies with existing federal innovation awards to strengthen commercialization momentum.

AIBiotech+6
$100K – $150K
Kentucky Cabinet for Economic Development — KY Innovation logo
Open

KSEF SBIR/STTR microAwards

🇺🇸KY Innovation · United States

Funds Kentucky small companies preparing SBIR/STTR proposals through microAwards.

AIBiotech+10
$5K
Montana Department of Commerce logo
Open

Montana SBIR/STTR Matching Funds

🇺🇸MT Commerce · United States

Funds matching support for Montana small businesses advancing federal innovation projects into additional commercialization stages.

AIBiotech+5
$30K
Innovate Mississippi logo
Open

MS-FAST SBIR/STTR Phase 0 — Proposal Prep Grant

🇺🇸Innovate MS · United States

Supports Mississippi small businesses by funding proposal preparation for national commercialization and research pathways.

$3K
National Aeronautics and Space Administration logo
Open

NASA SBIR/STTR Phase III — Sole-Source

🇺🇸NASA · United States

Offers direct follow-on commercialization agreements for United States space firms after successful early-space awards.

AerospaceAI+6
Office of Naval Research logo
Open

Navy SBIR/STTR — Seed (ONR-administered)

🇺🇸ONR · United States

Supports small-business naval technology projects through multiple annual DoD research milestones.

DefenseAI+5
National Center for Advancing Translational Sciences logo
Open

NCATS SBIR Phase I

🇺🇸NCATS · United States

Supports small businesses testing translational science tools and technologies through early feasibility and commercialization groundwork.

BiotechMedtech+1
$306K
National Center for Advancing Translational Sciences logo
Open

NCATS SBIR Phase II

🇺🇸NCATS · United States

Backs small businesses scaling proven translational findings into applied solutions and early market readiness.

BiotechMedtech+1
$2M
NIH National Cancer Institute logo
Open

NCI SBIR/STTR Omnibus (Next Receipt 5)

🇺🇸NCI · United States

Supports small businesses developing cancer technologies through national NIH collaboration pathways.

BiotechMedtech+3
$300K – $2M
Nebraska Department of Economic Development logo
Open

Nebraska SBIR/STTR Match

🇺🇸NE DED · United States

Funds Nebraska small businesses to extend federal innovation milestones with state matching support.

NIH National Eye Institute logo
Open

NEI SBIR Phase I — Feasibility

🇺🇸NEI · United States

Supports United States. small businesses testing vision concepts through feasibility-focused grants.

MedtechBiotech+3
$296K
NIH National Eye Institute logo
Open

NEI SBIR Phase II — R&D

🇺🇸NEI · United States

Supports United States. small businesses scaling vision concepts into full development pathways.

MedtechBiotech+3
$2.0M
NIH National Eye Institute logo
Open

NEI STTR Phase I — Feasibility

🇺🇸NEI · United States

Funds small business and research-partner teams on feasibility vision tools for future commercialization.

MedtechBiotech+3
$296K

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