Grants by programme

SBIR and STTR grants

SBIR and STTR are the United States' seed fund for small companies with a technical idea a federal agency wants to see built. Each agency runs its own calls under the same rules, so the openings are scattered across a dozen sites. This page gathers every one the catalogue tracks, open calls first, from the health, science, space, energy and defence agencies down to the state programmes that top up a federal award.

Showing 73-96 of 160 grants

Maryland Technology Development Corporation (TEDCO) logo
Open

SBIR/STTR Matching Funds

๐Ÿ‡บ๐Ÿ‡ธTEDCO ยท United States

Supports Maryland technology companies through State Matching Funds by sharing part of their matching requirements for federal opportunities.

New Mexico Economic Development Department logo
Open

New Mexico Tech Research Collaborative SBIR Match (NMSBA)

๐Ÿ‡บ๐Ÿ‡ธNM EDD ยท United States

Funds New Mexico teams by matching technology research development with support for product scaling.

AerospaceBiotech+2
$25K โ€“ $400K
National Institutes of Health logo
Scheduled

Limited Competition: NIH Research Evaluation and Commercialization Hubs (REACH)

๐Ÿ‡บ๐Ÿ‡ธNIH ยท United States

Funds five academic hubs that fund proof-of-concept work and coach researchers toward founding a biomedical company.

Biotech
Nov'26
National Institutes of Health logo
Scheduled

Small Business Transition Grant for New Entrepreneurs (R41/R42)

๐Ÿ‡บ๐Ÿ‡ธNIH ยท United States

Funds a first STTR grant and entrepreneurial mentoring for a scientist who partners with a nonprofit institution and has never led research funding before.

Biotech
Jan'27
National Institutes of Health logo
Scheduled

Small Business Transition Grant for New Entrepreneurs (R43/R44)

๐Ÿ‡บ๐Ÿ‡ธNIH ยท United States

Funds a first SBIR grant and hands-on entrepreneurial mentoring for a scientist who has never led independent research funding before.

Biotech
Jan'27
National Science Foundation logo
Between cycles

NSF SBIR Phase I

๐Ÿ‡บ๐Ÿ‡ธNSF ยท United States

Funds United States deep-tech startups demonstrating scientific feasibility of novel science and engineering innovations.

AIAgritech+13
$150K โ€“ $305K
National Science Foundation logo
Between cycles

NSF STTR Phase I

๐Ÿ‡บ๐Ÿ‡ธNSF ยท United States

Funds United States deep-tech startups partnering with nonprofit research institutions for early-stage feasibility studies.

AIAgritech+13
$150K โ€“ $305K
National Science Foundation logo
Between cycles

NSF SBIR/STTR Fast-Track Pilot

๐Ÿ‡บ๐Ÿ‡ธNSF ยท United States

Supports United States deep-tech startups through a combined early and continuation development route.

AIAgritech+13
$800K โ€“ $1.6M
National Science Foundation logo
Between cycles

NSF SBIR Phase II

๐Ÿ‡บ๐Ÿ‡ธNSF ยท United States

Funds United States deep-tech startups extending proven early projects into substantial technology development.

AIAgritech+13
$500K โ€“ $1.3M
National Science Foundation logo
Between cycles

NSF STTR Phase II

๐Ÿ‡บ๐Ÿ‡ธNSF ยท United States

Funds United States deep-tech projects that continue with nonprofit research partners after successful initial feasibility work.

AIAgritech+13
$500K โ€“ $1.3M
US Department of Energy logo
Between cycles

DOE SBIR Phase I

๐Ÿ‡บ๐Ÿ‡ธDOE ยท United States

Funds U.S. for-profit small businesses establishing technical feasibility of innovative technologies across DOE priority areas including advanced manufacturing, critical materials, and quantum information science.

AIBiotech+6
US Department of Energy logo
Between cycles

DOE SBIR Phase II

๐Ÿ‡บ๐Ÿ‡ธDOE ยท United States

Funds U.S. small businesses advancing energy and science technologies from proven feasibility into prototype development through DOE's Phase II SBIR award.

Energy TechAdvanced Materials+8
U.S. Department of Education logo
Between cycles

ED/IES SBIR Phase I

๐Ÿ‡บ๐Ÿ‡ธED ยท United States

Funds for-profit small businesses developing and evaluating new education technology prototypes.

AIMedtech+3
$250K
U.S. Department of Education logo
Between cycles

ED/IES SBIR Phase II

๐Ÿ‡บ๐Ÿ‡ธED ยท United States

Funds for-profit small businesses completing full-scale development and evaluation of education technology products.

AIMedtech+3
$1M
NASA Space Technology Mission Directorate logo
Between cycles

NASA SBIR Phase II

๐Ÿ‡บ๐Ÿ‡ธNASA STMD ยท United States

Funds U.S. small businesses developing and demonstrating technology innovations that advance NASA missions, following a successful Phase I feasibility award.

AerospaceAI+10
$1.3M
NASA Space Technology Mission Directorate logo
Between cycles

NASA STTR Phase II

๐Ÿ‡บ๐Ÿ‡ธNASA STMD ยท United States

Funds U.S. small businesses and their research institution partners developing and demonstrating technology innovations through NASA's STTR Phase II award.

AerospaceAI+7
Air Force Office of Scientific Research logo
Between cycles

AFOSR STTR Phase I

๐Ÿ‡บ๐Ÿ‡ธAFOSR ยท United States

Offers small business and institution teams early research support for foundational Air Force concepts.

AerospaceAI+7
$60K โ€“ $100K
Air Force Office of Scientific Research logo
Between cycles

AFOSR STTR Phase II

๐Ÿ‡บ๐Ÿ‡ธAFOSR ยท United States

Supports small business teams extending validated concepts toward robust defense development.

AerospaceAI+7
$750K
AFWERX logo
Between cycles

AFWERX Specific Topic SBIR Release 1

๐Ÿ‡บ๐Ÿ‡ธAFWERX ยท United States

Supports small business technology opportunities through focused Air Force innovation calls.

AerospaceAI+5
$200K โ€“ $2M
AFWERX logo
Between cycles

AFWERX Specific Topic SBIR Release 2

๐Ÿ‡บ๐Ÿ‡ธAFWERX ยท United States

Supports a second focused set of Air Force small-business technology opportunities in emerging domains.

AerospaceAI+5
$200K โ€“ $2M
AFWERX logo
Between cycles

AFWERX Specific Topic STTR Release 1

๐Ÿ‡บ๐Ÿ‡ธAFWERX ยท United States

Supports research institution partnerships in Air Force technical areas through targeted collaboration pathways.

AerospaceAI+5
$200K โ€“ $2M
New Jersey Economic Development Authority logo
Between cycles

CSIT SBIR/STTR Direct Financial Assistance โ€” Phase 5

๐Ÿ‡บ๐Ÿ‡ธNJEDA ยท United States

Funds New Jersey small businesses to match early-stage federal innovation awards and bridge development costs.

AIBiotech+5
$25K โ€“ $50K
DHS Science and Technology Directorate logo
Between cycles

DHS SBIR Phase I

๐Ÿ‡บ๐Ÿ‡ธDHS S&T ยท United States

Supports small businesses addressing homeland security needs with early feasibility innovation in cybersecurity, border operations, and safety-critical tools.

CybersecurityDefense+4
$175K
DHS โ€” Department of Homeland Security logo
Between cycles

DHS Small Business Innovation Research Program

๐Ÿ‡บ๐Ÿ‡ธDHS ยท United States

Funds U.S. small businesses developing homeland security technologies through DHS SBIR grants.

DefenseCybersecurity+4
$1.5M

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