SBIR and STTR grants
SBIR and STTR are the United States' seed fund for small companies with a technical idea a federal agency wants to see built. Each agency runs its own calls under the same rules, so the openings are scattered across a dozen sites. This page gathers every one the catalogue tracks, open calls first, from the health, science, space, energy and defence agencies down to the state programmes that top up a federal award.
Showing 49-72 of 160 grants
NIH/CDC/FDA SBIR & STTR Parent Grants
🇺🇸NIH/CDC/FDA · United States
Funds US small businesses developing health, biomedical and diagnostic innovations toward clinical translation through NIH, CDC and FDA SBIR/STTR awards.
NIMH SBIR/STTR
🇺🇸NIMH · United States
Supports United States. small businesses building mental health technologies through recurring NIH pathways.
NINDS SBIR Phase I
🇺🇸NINDS · United States
Funds small-business feasibility research for neuroscience technologies advancing toward later commercialization in the United States.
NINDS STTR Phase I
🇺🇸NINDS · United States
Supports small businesses and neuroscience teams pairing with research institutions.
NIMHD SBIR Phase IIB Strategic Breakthrough Award
🇺🇸NIMHD · United States
Funds prior NIH SBIR and STTR Phase II small businesses bridging later-stage R&D to commercialization.
NIMHD SBIR/STTR Commercialization Readiness Pilot
🇺🇸NIMHD · United States
Funds NIH-funded small businesses moving SBIR or STTR projects from late-stage development to commercialization.
NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award
🇺🇸NIMH · United States
Funds a small business already through NIH SBIR Phase II to cross the gap to commercialisation. A cost share is required.
SBIR/STTR Commercialization Readiness Pilot (CRP) Program
🇺🇸NIH · United States
Funds late-stage R&D and technical work — trials, manufacturing scale-up, regulatory support — to finish a small business's NIH SBIR or STTR project.
Army SBIR Phase I
🇺🇸Army · United States
Funds United States Army-focused small businesses demonstrating technology feasibility for soldier and mobility needs.
Army SBIR Phase II
🇺🇸Army · United States
Supports United States Army-aligned innovators advancing validated technologies toward deployable military-ready systems.
DARPA SBIR Phase I
🇺🇸DARPA · United States
Funds United States small businesses validating high-risk defense science concepts for practical technical development.
DARPA SBIR Phase II
🇺🇸DARPA · United States
Supports United States defense innovators building on validated concepts into advanced prototypes and field testing.
AEDC SBIR Matching Grant
🇺🇸AEDC · United States
Funds Arkansas firms by co-financing federal research commercialization efforts to strengthen real-world implementation.
AFOSR STTR
🇺🇸AFRL · United States
Funds collaborative basic research pathways for technology transfer from concept through scalable prototypes.
AFWERX Open Topic SBIR/STTR
🇺🇸AFWERX · United States
Offers AFWERX open topic support for United States small businesses with dual use ideas through an always open route.
Defense Health Agency SBIR Phase I
🇺🇸DHA · United States
Funds United States defense medical innovators at feasibility stage for life-changing military health technologies.
Defense Health Agency SBIR Phase II
🇺🇸DHA · United States
Supports United States defense health teams maturing validated medical technologies toward practical military use.
DHS SBIR Phase II (invite-only)
🇺🇸DHS S&T · United States
Supports small businesses in the United States advancing proven homeland security prototypes in a second-stage federal programme.
DoD SBIR/STTR
🇺🇸DoD · United States
Supports small business and non-traditional teams across defense components in a shared topic flow.
DOE SBIR/STTR ASCR Topics
🇺🇸DOE ASCR · United States
Offers innovation teams support in advanced computing and hardware-oriented technologies.
ED/IES SBIR Phase II (Standard — Phase I Graduates)
🇺🇸IES · United States
Supports United States education small businesses turning early feasibility into commercially viable offerings.
Innovation Partnership (IPart) SBIR/STTR Proposal Support
🇺🇸PA DCED · United States
Offers Pennsylvania small businesses free proposal reviews, training seminars, and travel support for federal innovation applications.
Kentucky SBIR/STTR Match — Phase I
🇺🇸KY Innovation · United States
Funds Kentucky companies with state matching support for early federally aligned innovation projects.
Kentucky SBIR/STTR Match — Phase II
🇺🇸KY Innovation · United States
Funds Kentucky companies with larger state matching support as innovation projects move toward commercialization.