NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders
Funds Phase I trials for heart, lung, blood and sleep disorders — and pays for the final preclinical work needed to start one.
The National Heart, Lung, and Blood Institute funds investigator-initiated Phase I clinical trials of diagnostics and therapeutics for heart, lung, blood and sleep disorders, in adults and children.
What makes this route unusual is what it pays for besides the trial. The award covers final-stage preclinical activities needed to make the trial possible — stability studies, shipping studies, site t…
Investigator-initiated Phase I clinical trials of diagnostic and therapeutic interventions for heart, lung, blood and sleep disorders in adults and children, together with the final-stage preclinical activities directly required to start the trial. Two-phase, milestone-driven.
Sign up free to see the funding breakdown
Sign up free to see the industries in scope
Sign up free to see the full eligibility
Sign up free to see how to apply
Sign up free to see what you submit
Sign up free to see how they score you
Sign up free to see the timeline
Sign up free to see where teams trip up
Guides for this application
All guides →NIH Biosketch Guide: Format, SciENcv Steps, and Examples
Learn what an NIH biosketch is, how the format works, what to prepare for SciENcv, and how startup teams should avoid common biosketch mistakes.
Write proposalHow to Write a Specific Aims Page
Learn how to write a specific aims page for NIH, SBIR-adjacent, and translational R&D grants, with structure, reviewer logic, examples, and common mistakes.
Where to applyGrants for Biotech Startups: NIH, NSF, SBIR/STTR, and Non-Dilutive Funding
A practical guide to grants for biotech startups, including NIH SBIR/STTR, NSF, translational funding, evidence, regulatory readiness, and budgets.
Write proposalHow to Write a Grant Proposal Reviewers Can Score
Learn how to write a grant proposal around reviewer criteria, evidence, work packages, budget logic, and commercialization for deeptech and R&D funding.
More from NIH
All grants from this funder →Nutrition Obesity Research Centers (NORCs)
🇺🇸NIH · United States
Funds shared research cores, pilot funding and a catalyst programme where a substantial nutrition or obesity research effort already exists.
Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults
🇺🇸NIH · United States
Funds a pilot trial of a behavioural sleep intervention for adolescents and young adults who have a mental health disorder or are at risk of one.
GREGoRi Data Coordination and Outreach Center
🇺🇸NIH · United States
Funds the one centre that coordinates a rare-disease genomics programme and gets its protocols, data and tools out to everybody else.
GREGoRi Innovation Projects
NIH · United States
Funds a genuinely new experimental or computational approach to finding the cause of a rare genetic disorder, where the current state of the art falls short.
GREGoRi Technology Integration Center
🇺🇸NIH · United States
Funds the centre that turns new molecular methods for rare-disease diagnosis into standards, best practices and a benchmarking dataset.
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases
🇺🇸NIH · United States
Funds studies that watch patients rather than treat them, in bone, joint, rheumatic and skin disease. No intervention allowed.
Similar grants
Browse the directory →
DoW Tick-Borne Disease Therapeutic/Diagnostic Research Award
🇺🇸MRDC / CDMRP · United States
Funds either a drug-discovery study or a clinical diagnostic approach for Lyme disease and other tick-borne diseases, aimed at something a clinic could use.
NCATS Clinical Trial Readiness for Rare Diseases
🇺🇸NCATS · United States
Funds U.S. researchers and companies generating natural history data, biomarkers, and outcome measures needed to design clinical trials for rare diseases.
INCLUDE Project — Clinical Trials Phased Awards
🇺🇸NICHD · United States
Funds phased clinical research programs for Down syndrome interventions through developmental and expansion awards.
NHMRC Clinical Trials and Cohort Studies Grants
🇦🇺NHMRC · Australia
Funds clinical trials and cohort studies in Australia addressing major evidence gaps in healthcare.
Clinical trials for advancing innovative interventions for neurodegenerative diseases
🇪🇺European Commission · European Union
Funds early clinical trials of safer, more effective interventions for non-rare neurodegenerative diseases.
Portable and versatile Point-of-care diagnostics
🇪🇺European Commission · European Union
Funds €5–7M projects that make point-of-care diagnostics more portable, versatile, accurate and useful in clinical practice.