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NIH Exploratory/Developmental Research Grant

Schizophrenia and related disorders during mid- to late-life (R21)

Funds short, exploratory work on how schizophrenia emerges and changes after 35 — the age group nearly all the research has skipped.

Most people living with schizophrenia are over 35 — some diagnosed decades ago and ageing with the illness, some diagnosed late. Almost all the research attention has gone to first-episode psychosis in young adults, and the result is that the mechanisms driving the illness in mid and late life are, in NIH's own words, poorly understood.

This notice funds translational work on that gap — two conne

Translational research into how schizophrenia and related disorders emerge and change during mid to late life, in both people diagnosed young and ageing with the illness and people first diagnosed later, and into the targets that work suggests for future prevention and treatment.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.7 Sept 2026
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.
Funding pooliThe total budget available across all awards in this round.

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Last verified: 25 Aug 2026Funder reference: PAR-25-040Source: www.grants.gov