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NIH Research Project Cooperative Agreement (U01)

Limited Competition: Renewal of Existing NINDS-Supported Clinical Trial Cooperative Agreement Awards

Funds the renewal of a neurology clinical trial the institute already supports, where finishing it needs more time and resources.

OpenNational Institutes of HealthUnited States

Clinical trials run long. Recruitment takes longer than planned, a site drops out, an interim look changes the protocol. This notice is the door for a trial that needs more of both to finish.

It is a limited competition, and the limit is simple: renewal applications from existing clinical trial cooperative agreement awards supported by the National Institute of Neurological Disorders and Stroke, …

Renewal applications from existing clinical trial cooperative agreement awards supported by the National Institute of Neurological Disorders and Stroke, where additional time and resources are needed to complete the trial. A clinical trial is required.

CycleiHow often this grant runs - e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.5 Nov 2027
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.-
Award typeiThe form of funding - grant, equity, loan, tax credit, etc.Cooperative agreement
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.-
Funding pooliThe total budget available across all awards in this round.-

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Guides for this application

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National Institutes of Health logo
Between cycles

Advanced Development of Informatics Technologies for Cancer Research and Management

NIH · United States

Funds the enhancement of a cancer informatics tool that has cleared prototyping, shows real promise, and has not yet been widely adopted.

AIBiotech
$50K – $600K
National Institutes of Health logo
Closed

Community Engagement Evaluation and Data Coordination (CEED) Hub to Advance Data and Practice Transformation for Optimizing Oral Health for All

🇺🇸NIH · United States

Funds a single hub that coordinates data, evaluation and operations for a consortium of community-based oral health research projects.

National Institutes of Health logo
Between cycles

Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03)

🇺🇸NIH · United States

Funds one small self-contained project for a scholar already inside the Clinical and Translational Science Award network, on the way to a first full award.

$50K
National Institutes of Health logo
Closed

Model-to-Clinic (M2C) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI)

NIH · United States

Funds the move of an imaging-centred multimodal AI tool from a trained and tested prototype towards real clinical use, as regulated device software.

AIMedtech
National Institutes of Health logo
Closed

PRIMED-AI: Data-to-Model Academic-Industrial Partnerships (D2M-AIP) for Precision Medicine with AI: Integrating Imaging with Multimodal Data

NIH · United States

Funds a company and an academic team to build and test an imaging-centred multimodal AI decision tool, developed as software that is a medical device.

AIMedtech
National Institutes of Health logo
Between cycles

Sustained Support for Informatics Technologies for Cancer Research and Management

NIH · United States

Funds the running costs and continued relevance of a cancer informatics tool that researchers already depend on.

AIBiotech
$50K – $600K
NIH Common Fund logo
Open

Complement-ARIE — Open Funding (Seed)

🇺🇸NIH Common Fund · United States

Supports development of human-based new approach methodologies replacing animal models in relevant research.

BiotechMedtech+1
Army Medical Research and Development Command logo
Open

DOW Combat Readiness - Medical Research Program Translational Research Award

🇺🇸MRDC / CDMRP · United States

Funds translational trauma-care research moving a mature idea toward better survival and care right after injury.

BiotechMedtech
Nov'26
National Institute for Occupational Safety and Health logo
Open

NIOSH WTC Health Program — U01 Cooperative Research

🇺🇸NIOSH · United States

Funds clinical research into health outcomes linked to complex urban disasters.

BiotechMedtech
$550KDec'26
NIH Common Fund logo
Open

NIH Common Fund Venture Program — Open Funding (Seed)

🇺🇸NIH Common Fund · United States

Supports high-potential short- to medium-range initiatives that can seed major breakthroughs.

BiotechMedtech+3
$15M
Centers for Disease Control and Prevention logo
Open

Emerging Infections Network - Research for Preventing, Detecting, and Managing Travel-associated Infectious Diseases

🇺🇸CDC · United States

Funds surveillance and research networks that detect, diagnose and track infectious diseases among international travelers.

Biotech
$1.8M – $6MNov'26
Army Medical Research and Development Command logo
Open

DoW Joint Warfighter Medical, Military Medical Research and Development Award

🇺🇸MRDC / CDMRP · United States

Funds a continuation phase for medical research that already holds earlier DOD or DOW funding, from preclinical work through clinical trials.

BiotechMedtech
Nov'26