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NIH Research Project Grant

Mood and Psychosis Symptoms during the Menopause Transition (R01)

Funds translational work on the neurobiology behind mood and psychotic symptoms during the menopause transition, aimed at treatment targets.

The menopause transition is a period of large hormonal change, and a period when mood and psychotic disorders appear or get worse. Very little research connects the two mechanistically, which is what this notice funds.

The disorders named are perimenopausal depression, generalised anxiety disorder, bipolar disorder and schizophrenia.

The work is translational, and the stated purpose is understan

Translational research on the emergence and worsening of mood and psychotic disorders — including perimenopausal depression, generalised anxiety disorder, bipolar disorder and schizophrenia — during the menopause transition, on the underlying neurobiological and behavioural mechanisms, to identify targets for future novel treatment interventions. Clinical trials are optional.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.7 Jan 2028
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.
Funding pooliThe total budget available across all awards in this round.

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Last verified: 25 Aug 2026Funder reference: PAR-25-281Source: www.grants.gov