Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R01)
Funds studies using electrodes already implanted in people to record and stimulate directly, answering mental health questions no scan can reach.
Some patients have electrodes inside their brain for clinical reasons — epilepsy monitoring, deep brain stimulation. While those electrodes are in place, they can record and stimulate with a precision no scan comes close to. This notice funds using that window.
What invasive recording offers is described plainly: an unparalleled view of the neural circuitry and dynamics underlying complex moods, …
Invasive neural recording and stimulation studies in humans addressing mental health-relevant questions about neural circuitry and dynamics underlying moods, emotions, cognitive functions and behaviours at high spatial and temporal resolution, including causal tests by modulating network dynamics through the same electrodes, and development of new technologies and therapeutic approaches. Clinical trials are optional.
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