National Institutes of Health logo
NIH Specialized Center (P50)

National Biomedical Research Centers

Funds specialised biomedical research centers built to replace animal testing with new human-based research models.

Whole-animal research is expensive, slow, and increasingly something funders expect a project to justify rather than default to. This notice funds centres built to give researchers a genuine alternative, at national scale.

National Biomedical Research Centers, or NBRCs, provide scientific expertise, advanced equipment, infrastructure and well-characterised research models to researchers nationall

Specialised biomedical research centers (P50) providing shared scientific expertise, advanced equipment, infrastructure and well-characterised research models to researchers nationally, with an explicit mandate to develop innovative human-based New Approach Methodologies (NAMs) that reduce, refine and replace whole-animal use. Open competition, including at centres with existing nonhuman primate colonies. Clinical trials are allowed only as human-based NAMs.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Multiple per year
Next deadlineiThe next date applications are due. Rolling means you can apply any time.25 Jan 2027
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.
Funding pooliThe total budget available across all awards in this round.

Sign up free to see the funding breakdown

Sign up free to see the industries in scope

Sign up free to see the full eligibility

Sign up free to see how to apply

Sign up free to see what you submit

Sign up free to see how they score you

Sign up free to see the timeline

Sign up free to see where teams trip up

Last verified: 25 Aug 2026Funder reference: PAR-28-017Source: www.grants.gov