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NIH Research Project with Complex Structure (RM1)

High Priority HIV and Substance Use Research (RM1)

Funds team or individual research at the join between HIV and substance use, with preliminary data required in the application.

OpenNational Institutes of HealthUnited States

HIV and drug use are entangled — in transmission, in staying on treatment, in who gets reached at all — and research that treats them separately misses most of it. This notice funds the join.

What is wanted is innovative projects that could open new areas of HIV and AIDS research, or lead to new routes to prevention, treatment and cure of HIV among people who use drugs.

The scope of method is wi…

High-priority research at the intersection of HIV and substance use, from basic science to clinical and implementation research, opening new areas of HIV and AIDS research or new routes to prevention, treatment and cure among people who use drugs, within the published National Institutes of Health HIV and AIDS research priorities. A detailed research plan, preliminary data and a clear nexus with substance use are required.

CycleiHow often this grant runs — e.g. annually, on a rolling basis, or a one-off call.Annual
Next deadlineiThe next date applications are due. Rolling means you can apply any time.5 Mar 2027
Decision timeiTypical time from the deadline to the funder's decision.26 weeks
Project durationiHow long the funded work is expected to run.—
Award typeiThe form of funding — grant, equity, loan, tax credit, etc.Grant
Match fundingiThe share of project costs you must cover yourself. 0% = fully funded.—
Funding pooliThe total budget available across all awards in this round.—

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Last verified: 25 Aug 2026Funder reference: RFA-DA-25-060Source: www.grants.gov