Grants of $250K to $1M
Explore grants with an award between $250,000 and $1 million. This directory lists funding for product development, applied research, feasibility and early commercialization, the range where most national innovation programs and second-phase awards sit, with the deadline and eligibility on every listing.
Showing 145-168 of 694 grants
Reissue of RFA-FD-23-001- Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases
FDA · United States
Funds clinical trials testing whether a product works and is safe for a rare disease, aimed at a new indication or a labeling change.
INCLUDE Project: Transformative Research Awards for Down syndrome
NIH · United States
Funds bold, unconventional Down syndrome research that could open an entirely new scientific or clinical direction.
Seed Instrumentation Support (SIS) Program
🇺🇸NIH · United States
Funds buying one commercially available research instrument new to the institution, shared across users, from $50,000 up to $400,000.
Defense Security Cooperation University - Research Grants
🇺🇸DoD · United States
Funds security cooperation and irregular warfare research through DSCU's two open, standing tracks for researchers of any kind.
Transformative Non-Invasive/Minimally Invasive Technologies for Imaging the Olfactory System Across Scales (R01 CT Optional)
🇺🇸NIH · United States
Funds new non-invasive or minimally invasive ways to image the human sense of smell, from nose to brain.
US-Ireland R&D Partnership
🇮🇪HRB (Health Research Board Ire · Ireland
Connects United States and United Kingdom researchers through joint biomedical innovation grants.
CCRP Initiative: Promoting a Basic Understanding of Chemical Threats to Skin
🇺🇸NIH · United States
Funds basic research into how public-health chemical threats injure skin, aiming at future broad-spectrum countermeasures.
Early Immune System Development and Ontogeny
NIH · United States
Funds research into how the immune system forms in the womb, infancy and early childhood, including under HIV or antiretroviral exposure.
Community-Based Participatory Research to Advance Data and Practice Transformation (ADAPT) for Optimizing Oral Health for All
🇺🇸NIH · United States
Funds community-based research testing policies and cross-sector partnerships that address the risk factors driving unequal oral disease.
The Metastasis Research Network (MetNet): MetNet Research Projects
NIH · United States
Funds a research project that plugs into NCI's Metastasis Research Network of systems-level cancer centers, up to $500,000.
Limited Competition: Instrumentation Grant Program for Resource-Limited Institutions
🇺🇸NIH · United States
Funds one shared scientific instrument, priced between $25,000 and $250,000, for a research institution with limited resources.
Advancing Bioinformatics, Translational Bioinformatics and Computational Biology Research
NIH · United States
Funds new bioinformatics, computational biology, or AI methods that turn messy biomedical datasets into usable knowledge.
Research Grants in Clinical Informatics
NIH · United States
Funds building and testing clinical informatics tools that turn health records, notes, and images into better care.
Bioengineering Research Grants (BRG)
NIH · United States
Funds small multidisciplinary teams applying bioengineering to a specific biomedical, translational or clinical problem, up to $500,000.
Causal Hypotheses on the Oral-Systemic Health Impacts of Human Behaviors among People with Chronic Conditions
🇺🇸NIH · United States
Funds research testing causal links between everyday human behaviors and oral-systemic health outcomes in people with chronic conditions.
NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement
🇺🇸NIH · United States
Funds prospective observational studies or biomarker-validation studies that need new data or biospecimen collection, through a cooperative agreement.
Global-Asia Digital Bond Grant Scheme (G-ADBGS)
🇸🇬MAS · Singapore
Provides external review support for digital bond issuance using distributed ledger structures in Singapore.
Heritage Revival Fund
🇬🇧AHF · United Kingdom
Support for community ownership, adaptation and reuse of historic buildings.
Community and Environment Fund (CEF) and Business and Local Economy Fund (BLEF)
🇬🇧HS2 · United Kingdom
Grants for not-for-profit projects addressing HS2 construction disruption
Army SBIR Phase I
🇺🇸Army · United States
Funds United States Army-focused small businesses demonstrating technology feasibility for soldier and mobility needs.
DARPA SBIR Phase I
🇺🇸DARPA · United States
Funds United States small businesses validating high-risk defense science concepts for practical technical development.
Deep Tech Accelerator (DTA)
🇫🇮Business Finland · Finland
Funds young Finnish deep-tech companies commercialising research results through a phased grant-and-loan package.
ENEA Proof of Concept Program
ENEA · Italy
Funds companies moving ENEA laboratory technologies toward industrial use through co-funded proof-of-concept projects.
NCATS STTR Phase I
🇺🇸NCATS · United States
Funds U.S. small businesses and their nonprofit research partners to conduct feasibility studies on translational science innovations toward commercialization.