Synthetic Biology grants in the United States
Explore Synthetic Biology grants for companies in the United States. This list brings together funding for engineered biology, biomanufacturing, biofoundries and bio-based materials from US innovation agencies, research funders and foundations, international programs open to applicants in the United States, and competitions any company can enter, with the deadline, award size and eligibility on every listing. Grants aimed at Synthetic Biology in the United States come first.
Showing 1-24 of 288 grants
DARPA BTO Office-wide BAA
🇺🇸DARPA · United States
Funds United States convergence work in biology, neurotechnology, and synthetic biology for strategic defense purposes.
R&D Tax Credit — Income Tax Credit (Section 41) — TY2025 / Filed
🇺🇸IRS · United States
Supports established United States companies with income tax credits tied to qualified innovation spending.
R&D Tax Credit — QSB Payroll Offset (Section 41) — TY2025 / Filed
🇺🇸IRS · United States
Supports United States small businesses through payroll tax offsets when they fund qualifying innovation activity.
AFRI Foundational and Applied Science
🇺🇸USDA NIFA · United States
Supports agriculture innovation across plant health, bioenergy, food safety, and rural systems through USDA research grants and extension.
ARPA-H SBIR/STTR
🇺🇸ARPA-H · United States
Funds United States small businesses bridging health and neuroscience technologies from feasibility into advanced development.
NCATS Clinical Trial Readiness for Rare Diseases
🇺🇸NCATS · United States
Funds U.S. researchers and companies generating natural history data, biomarkers, and outcome measures needed to design clinical trials for rare diseases.
NIMHD Parent SBIR Grant
🇺🇸NIMHD · United States
Funds United States small businesses developing health-disparities technologies through NIH SBIR grants.
NIMHD Parent STTR Grant
🇺🇸NIMHD · United States
Funds United States small businesses partnering with nonprofit research institutions on health-disparities technologies.
NCATS Preclinical Proof of Concept Studies for Rare Diseases
🇺🇸NCATS · United States
Funds U.S. researchers and companies conducting preclinical efficacy studies to advance therapeutic candidates for rare diseases toward IND applications.
BARDA BAA (through
🇺🇸BARDA · United States
Supports teams developing countermeasure technologies for CBRN, diagnostics, and readiness-focused therapeutics through BARDA BAA.
BARDA DRIVe ImmuneChip+ (through
🇺🇸BARDA · United States
Supports creators of immune-enabled organ-on-chip systems and biosensing manufacturing for critical health technology challenges.
NIMHD SBIR Phase IIB Strategic Breakthrough Award
🇺🇸NIMHD · United States
Funds prior NIH SBIR and STTR Phase II small businesses bridging later-stage R&D to commercialization.
NIMHD SBIR/STTR Commercialization Readiness Pilot
🇺🇸NIMHD · United States
Funds NIH-funded small businesses moving SBIR or STTR projects from late-stage development to commercialization.
ARPA-H Mission Office ISOs
🇺🇸ARPA-H · United States
Supports United States mission teams with boundary-pushing health initiatives beyond existing programme limits.
ARPA-H Program ISOs (topic-specific)
🇺🇸ARPA-H · United States
Funds United States health initiatives through topic-focused pathways across multiple mission areas and agencies.
NCATS STTR Phase I
🇺🇸NCATS · United States
Funds U.S. small businesses and their nonprofit research partners to conduct feasibility studies on translational science innovations toward commercialization.
NCATS STTR Phase II
🇺🇸NCATS · United States
Funds U.S. small businesses and their nonprofit research partners to continue and expand translational R&D begun in STTR Phase I toward a commercial product.
ARPA-H Initiatives & Sprints
🇺🇸ARPA-H · United States
Runs fast-turnaround health technology opportunities in United States for high-potential exploratory science and engineering.
CFF Mission Ventures Industry Investment
🇺🇸CFF · United States
Offers startup and industry teams with commercialization support for CFF Mission Ventures Industry Investment in biotechnology, medical technology, and synthetic biology.
Core Research in Biological Sciences (BIO Core)
🇺🇸NSF · United States
Funds biology at any scale, from molecules to biomes — $280 million across roughly 300 awards, with no deadline.
Engineering (ENG): Chemical, Bioengineering, Energy, and Transport Systems (CBET)
🇺🇸NSF · United States
Funds foundational engineering research on chemical processes, biological systems, energy and water, and transport phenomena.
Engineering Biological and Biomedical Systems (EBBS)
🇺🇸NSF · United States
Funds engineering of biology — biosensing, tissue and organ function, biomanufacturing — and lists plainly what it will not fund.
Montana STEP Export Grant
🇺🇸MT Commerce · United States
Funds Montana small businesses exporting deep-tech products internationally through reimbursement of trade shows, compliance testing, IP filings, e-commerce, and market research costs.
MTRAC AgBio Innovation Hub — Translational Grants
🇺🇸MSU · United States
Funds translational agriculture and biology research through Michigan innovation hubs serving university and nonprofit teams.