Global collaboration action for the development of TB drugs for therapy and chemoprophylaxis in adults and children in sub-Saharan Africa
Funds Phase IIa-and-later clinical trials of new or shorter TB drug and chemoprophylaxis regimens for adults and children in sub-Saharan Africa.
This is a two-stage Research and Innovation Action run by Global Health EDCTP3. On the full second-stage application, each of the three award criteria -- Excellence, Impact, and Quality and Efficiency of the implementation -- is scored out of 5, with individual thresholds of 4, 4 and 3, and an overall threshold of 12 out of 15; proposals clearing every threshold are funded within budget, with a po…
This call wants clinical trials that push new or improved TB drugs, shorter treatment regimens, or chemoprophylaxis toward registration, including for multidrug- and extensively drug-resistant TB. It also welcomes proposals combining TB post-exposure prophylaxis with leprosy prevention, since the two diseases share transmission routes and drug candidates. Preclinical work, vaccines, diagnostics and monoclonal antibodies are out of scope.
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