Accelerating the Development of Prophylactic Vaccines Against Neglected Tropical Diseases (NTDs) in Sub-Saharan Africa
Funds clinical trials of prophylactic vaccines against neglected tropical diseases such as schistosomiasis, leishmaniasis and leprosy in sub-Saharan Africa.
Full second-stage proposals are scored on the same three criteria used across other EDCTP3 topics: Excellence and Impact each need at least 4 out of 5, Quality and Efficiency of the Implementation needs at least 3 out of 5, and the combined score across all three must reach at least 12 out of 15 before a proposal is even considered for funding. Within that pool, the funding decision doesn't stop aโฆ
This topic wants early- or late-stage clinical trials of prophylactic vaccines against a named list of 16 neglected tropical diseases in sub-Saharan Africa, from Buruli ulcer and dengue to schistosomiasis, leprosy and trachoma; Chagas disease, scabies and snakebite envenoming are explicitly out of scope, as is implementation research. It wants data generated across the general population and, where relevant, pregnant women, newborns, children and people with co-infections, with a clear regulatory and access strategy.
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