Grants of $250K to $1M
Explore grants with an award between $250,000 and $1 million. This directory lists funding for product development, applied research, feasibility and early commercialization, the range where most national innovation programs and second-phase awards sit, with the deadline and eligibility on every listing.
Showing 49-72 of 731 grants
Prevention and Intervention Approaches for FASD (R34)
🇺🇸NIAAA · United States
Supports FASD prevention and intervention planning studies to establish feasibility and practical research direction.
HEAL Initiative: Studies to Enable Analgesic Discovery
🇺🇸NIH · United States
Funds the assays, screening and first characterisation that a pain drug discovery programme needs before it can start properly.
National Bycatch Reduction Engineering Program (BREP) - FY2026/27
🇺🇸NOAA · United States
Funds designing and testing fishing gear that reduces bycatch and post-release deaths in US commercial and recreational fisheries.
Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program
🇺🇸NIH · United States
Funds an organisation with few research resources to do research, improve its research environment, and build the office that administers grants.
BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS
🇺🇸NIH · United States
Funds a novel recording or modulation technology for the human central nervous system from proof of concept up to readiness for first-in-human studies.
Minor Use Minor Species Development of Drugs
FDA · United States
Funds the safety and effectiveness testing costs of getting a designated new animal drug through FDA approval.
Targeting RNA in Disease with Novel Technologies (TRDNT) Challenge
🇺🇸NIH · United States
Awards up to $13.1 million across three phases to US-based teams developing novel technologies that target RNA to treat human disease.
TRDNT Challenge Phase II: Prototype Development and Use Case Demonstration
🇺🇸NIH · United States
Pays up to $120,000 per Interim Milestone winner and up to $320,000 per Final Submission winner to US-based researchers, startups and institutions that build a working prototype technology able to target endogenous RNA in human disease.
Silvio O. Conte Digestive Diseases Research Core Centers
🇺🇸NIH · United States
Funds shared lab cores and shared facilities that let a digestive or liver disease research group at one institution work as a coordinated center.
BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain
🇺🇸NIH · United States
Funds exploratory human studies that record and stimulate neurons directly, using brain access that invasive procedures already create.
Critical Raw Materials Partnership (RAMP) Joint Call
🇸🇪Energimyndigheten (Swedish Ene · Sweden
Funds transnational consortia working on raw-material supply, use, and recycling projects through the RAMP joint call run by Energimyndigheten and Vinnova.
John R. Evans Leaders Fund
🇨🇦CFI · Canada
Funds Canadian investigator infrastructure for flagship science outcomes through national competition.
NCATS Clinical Trial Readiness for Rare Diseases
🇺🇸NCATS · United States
Funds U.S. researchers and companies generating natural history data, biomarkers, and outcome measures needed to design clinical trials for rare diseases.
Parkinson's Foundation Stanley Fahn Junior Faculty Award
🇺🇸Parkinson's Foundation · United States
Funds early-career Parkinson's disease researchers at United States and Canada institutions through independent investigator support.
Coupling, Energetics, and Dynamics of Atmospheric Regions
🇺🇸NSF · United States
Funds research on the upper atmosphere — from the middle atmosphere through the thermosphere and ionosphere into the exosphere.
Opportunities for Collaborative Research at the NIH Clinical Center
NIH · United States
Funds a translational research project run jointly with NIH's own intramural investigators at the Clinical Center, up to $500,000.
Continuation of the Cardiovascular Repository for-Type 1 Diabetes (CARE-T1D) Consortium U01 (Open Competition)- Research
🇺🇸NIH · United States
Funds research into why cardiovascular disease develops in people with type 1 diabetes, through an open-competition consortium.
Commissioned Rehabilitative Services General Grant Scheme
🇬🇧MoJ · United Kingdom
Grants for non-profit rehabilitative services across probation regions.
Regional Improvement for Standards and Excellence (RISE) School Improvement Grant
🇬🇧DfE · United Kingdom
Targeted school improvement support arranged through RISE regional teams.
NCATS STTR Phase I
🇺🇸NCATS · United States
Funds U.S. small businesses and their nonprofit research partners to conduct feasibility studies on translational science innovations toward commercialization.
FY26 DEFENSE ESTABLISHED PROGRAM TO STIMULATE COMPETITIVE RESEARCH (DEPSCoR) - RESEARCH COLLABORATION (RC)
🇺🇸AFOSR · United States
Funds a first-time faculty investigator paired with an experienced DoD-funded mentor on defense-relevant research.
NCATS SBIR Phase I
🇺🇸NCATS · United States
Supports small businesses testing translational science tools and technologies through early feasibility and commercialization groundwork.
NEI SBIR Phase I — Feasibility
🇺🇸NEI · United States
Supports United States. small businesses testing vision concepts through feasibility-focused grants.
NEI STTR Phase I — Feasibility
🇺🇸NEI · United States
Funds small business and research-partner teams on feasibility vision tools for future commercialization.