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Funder · Federal agency

National Institutes of Health

Funds biomedical research nationwide, supporting university, nonprofit, and small business projects across major health initiatives.

United Stateswww.nih.gov
Annual funding$35.3B
Programs146
Active grants301
Total grants454

National Institutes of Health (NIH) is the medical-research arm of the U.S. Department of Health and Human Services and the world's largest public funder of biomedical research. It sits in Bethesda and moves about $35.3 billion a year through 27 Institutes and Centers.

Its cross-IC routes include SBIR and STTR, parent R01, R03, and R21 announcements, the HEAL Initiative, and the NIH Common Fund.

NIH Research Project Grant

Helps NIH Research Project Grant for established research programs for innovation and strategic advancement.

81 grants
Alcohol Treatment, Pharmacotherapy, and Recovery Research (R01)
Open
$500K pool·11 days
Modular R01s in Cancer Control and Population Sciences
Open
pool·498 days
Alcohol Health Services Research (R01)
Open
$500K pool·11 days
NIH Research Project Grant
Open
pool·498 days
NIH Research Project Grant
Open
pool·498 days
Advancing Healthcare for Older Adults from Populations that Experience Health Disparities
Open
pool·498 days
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases
Open
pool·67 days
Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants
Open
pool·48 days
Research Projects to Enhance Applicability of Mammalian Models for Translational Research
Open
$499K pool·11 days
Molecular Imaging of Inflammation in Cancer
Open
$500K pool·498 days
Interventions to Reduce Sleep Health Disparities
Open
pool·376 days
Cellular and Molecular Biology of Complex Brain Disorders (R01)
Open
pool·11 days
Schizophrenia and related disorders during mid- to late-life (R01)
Open
pool·11 days
Mechanisms that Impact Cancer Risk after Bariatric Surgery (R01)
Open
pool·498 days
Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R01)
Open
pool·11 days
Social disconnection and Suicide Risk in Late Life (R01)
Open
pool·11 days
Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R01)
Open
pool·133 days
CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System
Open
$300K pool·50 days
Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems
Open
$500K pool·133 days
National Cancer Institute's Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis
Open
$500K pool·133 days
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01)
Open
$350K pool·71 days
Interventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities
Open
pool·133 days
Computational Approaches to Curation at Scale for Biomedical Research Assets
Open
$250K pool·231 days
Laboratories to Optimize Digital Health
Open
pool·498 days
Dissemination and Implementation Research in Health (R01)
Open
pool·498 days
Clinical Characterization of Cancer Therapy-induced Adverse Sequelae and Mechanism-based Interventional Strategies
Open
pool·498 days
Assay development and screening for discovery of chemical probes, drugs or immunomodulators
Open
pool·11 days
Cancer Prevention and Control Clinical Trials Grant Program
Open
pool·133 days
Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy
Open
$500K pool·498 days
Full-Scale Hybrid Effectiveness-Implementation Trials for Mental Health Interventions
Open
pool·414 days
Pilot Hybrid Effectiveness-Implementation Trials for Mental Health Interventions
Open
pool·414 days
Confirmatory Efficacy Clinical Trials of Non-Pharmacological and Pharmacological Interventions for Mental Disorders
Open
pool·414 days
Screening and Functional Validation of Genomic Variants Associated with Human Congenital Anomalies
Open
pool·498 days
Focused Technology Research and Development
Open
pool·498 days
Pilot Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes
Open
pool·498 days
Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes
Open
pool·498 days
Population Approaches to Reducing Alcohol-related Cancer Risk
Open
pool·133 days
Natural History of Disorders Screenable in the Newborn Period
Open
pool·498 days
Investigator Initiated Innovation in Computational Genomics and Data Science (R01)
Open
pool·376 days
Personal Health Informatics for Delivering Actionable Insights to Individuals
Open
pool·133 days
Basic Research in Cancer Health Disparities (R01)
Open
pool·498 days
Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01)
Open
pool·70 days
Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R01)
Open
pool·446 days
NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions
Open
pool·82 days
Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth
Open
pool·82 days
NCCIH Natural Product Mid Phase Clinical Trial
Open
$350K pool·78 days
New Approaches for Measuring Brain Changes Across Longer Timespans (R01)
Open
pool·253 days
Mood and Psychosis Symptoms during the Menopause Transition (R01)
Open
pool·498 days
Innovative Mental Health Services Research Not Involving Clinical Trials
Open
pool·498 days
Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R01)
Open
pool·498 days
Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R01)
Open
pool·498 days
Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R01)
Open
pool·498 days
Interventions to Address Disparities in Liver Diseases and Liver Cancer
Open
pool·498 days
Accelerating Solutions to Improve Access and Quality of Empirically-Supported Practices for Youth Mental Health
Open
pool·133 days
Risk and Protective Factors of Family Health and Family Level Interventions
Open
pool·254 days
Stephen I. Katz Early Stage Investigator Research Project Grant
Open
pool·729 days
Toward Translation of Nanotechnology Cancer Interventions (TTNCI)
Open
pool·445 days
Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment
Open
$499K pool·498 days
Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment
Open
$499K pool·498 days
Early Immune System Development and Ontogeny
Open
pool·801 days
Ethical, Legal and Social Implications (ELSI) Research
Open
pool·83 days
Intervention Research to Improve Native American Health (R01)
Open
pool·133 days
Screening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities
Open
pool·253 days
Advancing Bioinformatics, Translational Bioinformatics and Computational Biology Research
Open
$2.5M pool·921 days
Research Grants in Clinical Informatics
Open
$2.5M pool·921 days
Bioengineering Research Grants (BRG)
Open
pool·1043 days
CCRP Initiative: Promoting a Basic Understanding of Chemical Threats to Skin
Open
pool·801 days
Discovery of in vivo Chemical Probes for the Nervous System
Open
pool·190 days
Stimulating Hematology Investigation: New Endeavors (SHINE)
Open
pool·497 days
High Priority HIV and Substance Use Research (R01)
Open
pool·191 days
Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids
Open
$300K pool·448 days
Accelerating the Pace of Substance Use Research Using Existing Data (R01)
Open
pool·463 days
BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain
Open
pool·438 days
NIDCD Research Grants for Translating Basic Research into Clinical Practice
Open
$500K pool·411 days
In Vivo High-Resolution Imaging for Inner Ear Visualization
Open
$500K pool·35 days
Transformative Non-Invasive/Minimally Invasive Technologies for Imaging the Olfactory System Across Scales (R01 CT Optional)
Open
$2M pool·725 days
Supporting Talented Early Career Researchers in Genomics
Open
pool·183 days
BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain
Open
pool·165 days
Addressing Methodological Challenges with Clinical Trials of Rapid-Acting Psychotropic Interventional Drugs (RAPIDs)
Open
$5.5M pool·45 days
Advancing Research on Empirically-Supported Interventions for Older Adults Living with Serious Mental Illness (SMI)
Open
$3M pool·49 days
INCLUDE Project: Transformative Research Awards for Down syndrome
Open
$3M pool·658 days
NIH Exploratory/Developmental Research Grant

Helps NIH Exploratory and Developmental Research Grant for novel ideas and preliminary studies.

32 grants
Exploratory Grants in Cancer Control
Open
pool·742 days
NIH Exploratory/Developmental Research Project Grant
Open
pool·498 days
NIH Exploratory/Developmental Research Project Grant
Open
pool·498 days
Cellular and Molecular Biology of Complex Brain Disorders (R21)
Open
pool·11 days
Schizophrenia and related disorders during mid- to late-life (R21)
Open
pool·11 days
Mechanisms that Impact Cancer Risk after Bariatric Surgery (R21)
Open
pool·498 days
Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R21)
Open
pool·11 days
Social disconnection and Suicide Risk in Late Life (R21)
Open
pool·11 days
Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK
Open
pool·446 days
Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R21)
Open
pool·133 days
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21)
Open
$200K pool·82 days
Cutting-Edge Basic Research Awards (CEBRA)
Open
$150K pool·349 days
NIDCD Early Career Research(ECR) Award
Open
pool·414 days
Dissemination and Implementation Research in Health (R21)
Open
pool·498 days
Investigator Initiated Innovation in Computational Genomics and Data Science (R21)
Open
pool·376 days
Basic Research in Cancer Health Disparities (R21)
Open
pool·446 days
Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21)
Open
pool·133 days
Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R21)
Open
$200K pool·446 days
New Approaches for Measuring Brain Changes Across Longer Timespans (R21)
Open
pool·253 days
Development of Animal Models and Related Biological Materials for Research
Open
$200K pool·498 days
Mood and Psychosis Symptoms during the Menopause Transition (R21)
Open
pool·498 days
Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R21)
Open
pool·498 days
Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21)
Open
$200K pool·498 days
Exploratory/Developmental Bioengineering Research Grants (EBRG)
Open
pool·498 days
Exploratory/Developmental Bioengineering Research Grants (EBRG)
Open
pool·498 days
NEI Research Grant for Vision-Related Secondary Data Analysis
Open
pool·415 days
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant
Open
pool·83 days
Expanding the Target Landscape by Drugging the Undruggable
Open
pool·539 days
Accelerating the Pace of Substance Use Research Using Existing Data (R21)
Open
pool·463 days
Early-Stage Dissemination and Implementation Research in Communication Disorders
Open
$1M pool·294 days
Using Archived Data and Specimen Collections to Advance Maternal and Pediatric HIV/AIDS Research (R21 CT Not Allowed)
Open
$1M pool·785 days
INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome
Open
$1M pool·658 days
NIH Phase 1 Exploratory/Developmental Grant (R61)

Funds Phase 1 Exploratory/Developmental Grant, NIH's R61 mechanism.

22 grants
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61)
Open
pool·67 days
Development of Biomarkers or Composite Biomarkers for Neurological and Neuromuscular Disorders
Open
pool·498 days
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders
Open
pool·133 days
Translational Neural Devices
Open
pool·154 days
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification
Open
$750K pool·419 days
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery
Open
$750K pool·419 days
Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33)
Open
pool·414 days
Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R61/R33)
Open
pool·414 days
Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33)
Open
pool·279 days
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies
Open
pool·419 days
NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award
Open
$350K pool·78 days
Effectiveness Trials to Test Mental Health System Interventions
Open
pool·414 days
Mind and Body Interventions to Restore Whole Person Health via Emotional Well-Being Mechanisms
Open
pool·650 days
Single-Site Investigator-Initiated Clinical Trials
Open
pool·798 days
Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research
Open
$5.1M pool·75 days
Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research
Scheduled
$5.4M pool
HEAL Initiative: Translating Addiction Epidemiology, Prevention, Treatment, and Recovery Research into Practice
Open
pool·897 days
BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain
Open
$6M pool·168 days
Catalyze: Product Definition for Small Molecules, Biologics and Combination Products - Target Identification and Validation, and Preliminary Product/Lead Series Identification
Open
pool·483 days
Catalyze Product Definition Medical Device prototype design/testing and disease target identification and assay development
Open
pool·483 days
HEAL Initiative: Studies to Enable Analgesic Discovery
Open
pool·141 days
INCLUDE Project: Clinical Trials Phased Awards for Down syndrome Research
Open
$3M pool·658 days
NIH Research Project Cooperative Agreement (U01)

Funds Research Project - Cooperative Agreements, NIH's U01 mechanism.

34 grants
NIDA Animal Genomics Program
Open
pool·168 days
Limited Competition: Renewal of Existing NINDS-Supported Clinical Trial Cooperative Agreement Awards
Open
pool·435 days
First in Human and Early Stage Clinical Trials of Novel Investigational Drugs or Neuromodulatory Device-based Interventions for Psychiatric Disorders
Open
pool·414 days
Utilizing the PLCO Biospecimens Resource to Bridge Gaps in Cancer Etiology and Early Detection Research
Open
pool·407 days
Integrating Biospecimen Science Approaches into Clinical Assay Development
Open
pool·379 days
Translational Efforts to Advance Gene-based Therapies for Ultra-Rare Neurological and Neuromuscular Disorders
Open
pool·407 days
NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders
Open
pool·417 days
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U01)
Open
pool·424 days
Opportunities for Collaborative Research at the NIH Clinical Center
Open
pool·191 days
Expanding the Therapeutic Pipeline for Treating and Preventing Alzheimer's Disease and Related Dementias: Preclinical Validation and Drug Discovery for Novel Candidate Targets
Between cycles
pool
The Metastasis Research Network (MetNet): MetNet Research Projects
Open
pool·818 days
Causal Hypotheses on the Oral-Systemic Health Impacts of Human Behaviors among People with Chronic Conditions
Open
pool·1043 days
NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement
Open
pool·1043 days
NIAID Clinical Trial Implementation Cooperative Agreement
Open
pool·1043 days
Research Opportunities in Cancer Epidemiology Cohort Studies
Open
pool·1043 days
Opportunities for Collaborative Research with the NIH Intramural Research Program
Scheduled
pool
Alzheimer's Drug-Development Program
Scheduled
pool
Canine Cancer Immunotherapy Network (K9CIN)
Scheduled
pool
Early-Stage Development of Informatics Technologies for Cancer Research and Management
Open
$2.4M pool·418 days
Cooperative Agreement for In Vivo High-Resolution Imaging for Inner Ear Visualization
Open
$500K pool·35 days
Community Engagement Evaluation and Data Coordination (CEED) Hub to Advance Data and Practice Transformation for Optimizing Oral Health for All
Open
$1M pool·53 days
Continuation of the Collaborative Islet Transplantation Registry
Between cycles
$700K pool
Continuation of the Cardiovascular Repository for-Type 1 Diabetes (CARE-T1D) Consortium U01 (Open Competition)- Research
Open
$6M pool·195 days
Optimal Treatment Strategies for use of Anti-Obesity Medications (AOMs) in Children and Adolescents Clinical Centers
Open
$3M pool·43 days
Multimodal AI to Accelerate Precision Medicine for Type 1 Diabetes
Scheduled
$5M pool
GREGoRi Data Coordination and Outreach Center
Open
$2M pool·64 days
GREGoRi Technology Integration Center
Open
$3M pool·64 days
GREGoRi Innovation Projects
Open
$7.5M pool·64 days
ancient DNA for Modern Genomics (aDMG) Research Projects
Scheduled
pool
BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development
Open
pool·292 days
Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access
Open
$40M pool·75 days
Genomic and Biologic Therapies for ADRD
Between cycles
$6M pool
BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies
Open
$10M pool·403 days
Development and Testing of a Multi-use Frameworks Playbook for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI)
Open
$2M pool·43 days
NIH Resource-Related Research Projects Cooperative Agreement (U24)

Funds Resource-Related Research Projects - Cooperative Agreements, NIH's U24 mechanism.

14 grants
NIH Phase 1 Exploratory/Developmental Cooperative Agreement (UG3)

Funds Phase 1 Exploratory/Developmental Cooperative Agreement, NIH's UG3 mechanism.

18 grants
Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System
Open
pool·356 days
NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention
Open
pool·84 days
NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement
Open
pool·497 days
NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3)
Open
pool·189 days
NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement
Open
pool·497 days
Seamless Early-Stage Clinical Drug Development (Phase 1 to 2a) for Novel therapeutic Agents for the Spectrum of Alzheimer's Disease (AD) and AD-related Dementias (ADRD)
Open
pool·84 days
Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award
Open
$650K pool·418 days
Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Women, and Persons with Disabilities
Open
pool·445 days
Blueprint MedTech Translator
Open
pool·519 days
Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose
Open
pool·725 days
Clinical Trials and Ancillary Studies Conducted within NIH-Funded Clinical Trial Research Networks
Scheduled
pool
Clinical Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials
Open
pool·798 days
Community-Based Participatory Research to Advance Data and Practice Transformation (ADAPT) for Optimizing Oral Health for All
Open
pool·812 days
Multi-Site Investigator-Initiated Clinical Trials
Scheduled
pool
BRAIN Initiative: Next-Generation Devices for Recording and Modulation in the Human Central Nervous System
Open
pool·32 days
HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain
Open
$11M pool·908 days
PRIMED-AI: Data-to-Model Academic-Industrial Partnerships (D2M-AIP) for Precision Medicine with AI: Integrating Imaging with Multimodal Data
Open
pool·53 days
Model-to-Clinic (M2C) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI)
Open
pool·53 days
US Department of Health and Human Services
Last verified: 26 May 2026Source: www.nih.gov